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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-128</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTICLES</subject></subj-group></article-categories><title-group><article-title>Фиксированные комбинации - оптимальная стратегия лечения пациентов с артериальной гипертензией. Новая комбинация b-блокатора и диуретика - Лодоз</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Остроумова</surname><given-names>О. Д.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Средняков</surname><given-names>А. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гусева</surname><given-names>Т. Ф.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГОУ ВПО МГМСУ Росздрава, Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>5</volume><issue>2</issue><fpage>8</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Остроумова О.Д., Средняков А.В., Гусева Т.Ф., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Остроумова О.Д., Средняков А.В., Гусева Т.Ф.</copyright-holder><copyright-holder xml:lang="en">Остроумова О.Д., Средняков А.В., Гусева Т.Ф.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/128">https://www.syst-hypertension.ru/jour/article/view/128</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">И.Е.Чазова, Л.Г.Ратова. Комбинированная терапия артериальной гипертонии. М.: Медиа Медика, 2007.</mixed-citation><mixed-citation xml:lang="en">И.Е.Чазова, Л.Г.Ратова. Комбинированная терапия артериальной гипертонии. М.: Медиа Медика, 2007.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">BENETOS A, COSOLI S, SAFAVIAN A, et al.: Efficacy, safety and effects on quality of life of Bisoprolol/Hydrochlorothiazide versus Amlodipine in elderly patients with systolic hypertension. Am Heart J 2000; 140: e14.</mixed-citation><mixed-citation xml:lang="en">BENETOS A, COSOLI S, SAFAVIAN A, et al.: Efficacy, safety and effects on quality of life of Bisoprolol/Hydrochlorothiazide versus Amlodipine in elderly patients with systolic hypertension. Am Heart J 2000; 140: e14.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">DeQUATTRO V, WEIR M. Bisoprolol fumarate/Hydrochlorothiazide 6.25 mg: A new low-dose option for first-line antihypertensive therapy. Advances in therapy 1993; 10 (5): 197-206.</mixed-citation><mixed-citation xml:lang="en">DeQUATTRO V, WEIR M. Bisoprolol fumarate/Hydrochlorothiazide 6.25 mg: A new low-dose option for first-line antihypertensive therapy. Advances in therapy 1993; 10 (5): 197-206.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">FRISHMAN WH, BRYZINSKI BS, COULSON LR, et al. A multifactorial trial design to assess combination therapy in hypertension: Treatment with Bisoprolol and Hydrochlorothiazide. Arch Intern Med. 1994; 154: 1461-1468.</mixed-citation><mixed-citation xml:lang="en">FRISHMAN WH, BRYZINSKI BS, COULSON LR, et al. A multifactorial trial design to assess combination therapy in hypertension: Treatment with Bisoprolol and Hydrochlorothiazide. Arch Intern Med. 1994; 154: 1461-1468.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">FRISHMAN WH, BURRIS JF, MROCZEK WJ, et al. First-line therapy option with low-dose Bisoprolol fumarate and low-dose Hydrochlorothiazide in patients with stage I and stage II systemic hypertension. J Clin Pharmacol. 1995; 35: 182-188.</mixed-citation><mixed-citation xml:lang="en">FRISHMAN WH, BURRIS JF, MROCZEK WJ, et al. First-line therapy option with low-dose Bisoprolol fumarate and low-dose Hydrochlorothiazide in patients with stage I and stage II systemic hypertension. J Clin Pharmacol. 1995; 35: 182-188.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">FRISHMAN WH. ZIAC National Hypertension Trial Report. March 1996.</mixed-citation><mixed-citation xml:lang="en">FRISHMAN WH. ZIAC National Hypertension Trial Report. March 1996.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">HABIB GB . Reappraisal of heart rate as a risk factor in the general population. Eur Heart J 1999; 1 (Suppl H): H2-H10.</mixed-citation><mixed-citation xml:lang="en">HABIB GB . Reappraisal of heart rate as a risk factor in the general population. Eur Heart J 1999; 1 (Suppl H): H2-H10.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">JNC VI/The Sixth Report of the Joint National Commitee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, NIH Publications 1997; No. 98-4080.</mixed-citation><mixed-citation xml:lang="en">JNC VI/The Sixth Report of the Joint National Commitee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, NIH Publications 1997; No. 98-4080.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">LEWIN AJ, LEUG MC, TARGUM S, et al. A clinical trial evaluating the 24-hour effects of Bisoprolol 5/Hydrochlorothiazide 6.25 combination in patients with mild-to-moderate hypertension. Clin Cardiol. 1993; 16: 732-736.</mixed-citation><mixed-citation xml:lang="en">LEWIN AJ, LEUG MC, TARGUM S, et al. A clinical trial evaluating the 24-hour effects of Bisoprolol 5/Hydrochlorothiazide 6.25 combination in patients with mild-to-moderate hypertension. Clin Cardiol. 1993; 16: 732-736.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">MOSER M, BLACK H. The role of combination therapy in the treatment of hypertension. Am J Hypertens 1998; 11: 73S-78S.</mixed-citation><mixed-citation xml:lang="en">MOSER M, BLACK H. The role of combination therapy in the treatment of hypertension. Am J Hypertens 1998; 11: 73S-78S.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">NEUTEL JM, ROLF CN, VALENTINE SN, et al. Low-dose combination therapy as first line treatment of mild-to-moderate hypertension: the efficacy and safety of Bisoprolol/6.25 HCTZ versus Amlodipine, Enalapril, and placebo. Cardiovasc Rev Rep. 1996; 17: 33-45.</mixed-citation><mixed-citation xml:lang="en">NEUTEL JM, ROLF CN, VALENTINE SN, et al. Low-dose combination therapy as first line treatment of mild-to-moderate hypertension: the efficacy and safety of Bisoprolol/6.25 HCTZ versus Amlodipine, Enalapril, and placebo. Cardiovasc Rev Rep. 1996; 17: 33-45.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">PAPADEMETRIOU V, NEUTEL J, NARAVAN P, et al. Comparison of Bisoprolol and low dose Hydrochlorothiazide combination with Losartan, alone or in combination with Hydrochlorothiazide, in the treatment of hypertension: a double blind, randomized, placebo controlled trial. Cardiovasc Rev Rep.; December 1998.</mixed-citation><mixed-citation xml:lang="en">PAPADEMETRIOU V, NEUTEL J, NARAVAN P, et al. Comparison of Bisoprolol and low dose Hydrochlorothiazide combination with Losartan, alone or in combination with Hydrochlorothiazide, in the treatment of hypertension: a double blind, randomized, placebo controlled trial. Cardiovasc Rev Rep.; December 1998.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">PRISANT LM, WEIR MR, PAPADEMETRIOU V, et al. Low-dose drug combination therapy: An alternative first-line approach to hypertension treatment. Am Heart J. 1995; 130: 359-366.</mixed-citation><mixed-citation xml:lang="en">PRISANT LM, WEIR MR, PAPADEMETRIOU V, et al. Low-dose drug combination therapy: An alternative first-line approach to hypertension treatment. Am Heart J. 1995; 130: 359-366.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">PRISANT LM, NEUTEL JM, PAPADEMETRIOU V, et al. Low-dose combination treatment for hypertension versus single-drug treatment - Bisoprolol/Hydrochlorothiazide versus Amlodipine, Enalapril, and placebo: Combined analysis of comparative studies. Am J Ther .1998; 5: 313-321.</mixed-citation><mixed-citation xml:lang="en">PRISANT LM, NEUTEL JM, PAPADEMETRIOU V, et al. Low-dose combination treatment for hypertension versus single-drug treatment - Bisoprolol/Hydrochlorothiazide versus Amlodipine, Enalapril, and placebo: Combined analysis of comparative studies. Am J Ther .1998; 5: 313-321.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">PRISANT LM, WEIR MR, FRISHMANWH, et al.: Self reported Sexual Dysfunction in Men and Woman Treated With Bisoprolol, Hydrochlorothiazide, Enalapril, Placebo, or Bisoprolol/Hydrochlorothiazide. J Clin Hypertens. 1999; 1:22-26.</mixed-citation><mixed-citation xml:lang="en">PRISANT LM, WEIR MR, FRISHMANWH, et al.: Self reported Sexual Dysfunction in Men and Woman Treated With Bisoprolol, Hydrochlorothiazide, Enalapril, Placebo, or Bisoprolol/Hydrochlorothiazide. J Clin Hypertens. 1999; 1:22-26.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">o PRISANT LM, MOSER M: Hypertension in the Elderly. Arch Intern Med. 2000; 160: 283-289.</mixed-citation><mixed-citation xml:lang="en">o PRISANT LM, MOSER M: Hypertension in the Elderly. Arch Intern Med. 2000; 160: 283-289.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">WEIR MR, PRISANT LM, PAPADEMETRIOU V et al. Antihypertensive therapy and quality of life. Influence of blood pressure reduction, adverse events and prior antihypertensive therapy. Am J Hypertens. 1996; 9: 854-859.</mixed-citation><mixed-citation xml:lang="en">WEIR MR, PRISANT LM, PAPADEMETRIOU V et al. Antihypertensive therapy and quality of life. Influence of blood pressure reduction, adverse events and prior antihypertensive therapy. Am J Hypertens. 1996; 9: 854-859.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
