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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-169</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTICLES</subject></subj-group></article-categories><title-group><article-title>Эффективность применения кандесартана при гипертонической болезнии нефрогенной артериальной гипертонии</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чихладзе</surname><given-names>Н. М.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сивакова</surname><given-names>О. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блинова</surname><given-names>Е. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сахнова</surname><given-names>Т. А.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колос</surname><given-names>И. П.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Литонова</surname><given-names>Г. Н.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чазова</surname><given-names>И. Е.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Институт клинической кардиологии им. А.Л.Мясникова ФГУ РКНПК Федерального агентства по высокотехнологичной медицинской помощи, Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>5</volume><issue>4</issue><fpage>43</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чихладзе Н.М., Сивакова О.А., Блинова Е.В., Сахнова Т.А., Колос И.П., Литонова Г.Н., Чазова И.Е., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Чихладзе Н.М., Сивакова О.А., Блинова Е.В., Сахнова Т.А., Колос И.П., Литонова Г.Н., Чазова И.Е.</copyright-holder><copyright-holder xml:lang="en">Чихладзе Н.М., Сивакова О.А., Блинова Е.В., Сахнова Т.А., Колос И.П., Литонова Г.Н., Чазова И.Е.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/169">https://www.syst-hypertension.ru/jour/article/view/169</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Andersson OK, Neldham S. The antihypertensive effect and tolerability of candesartan cilexetil, a new generation angiotensin II antagonist, in comparison with losartan. Blood Press 1998; 7: 53-9.</mixed-citation><mixed-citation xml:lang="en">Andersson OK, Neldham S. The antihypertensive effect and tolerability of candesartan cilexetil, a new generation angiotensin II antagonist, in comparison with losartan. Blood Press 1998; 7: 53-9.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bakris G, Gradman A, Reif M et al. Antihypertensive efficacy of candesartan in comparison to losartan: the CALM study. J Clin Hypertens (Greenwich) 2001; 3: 16-21.</mixed-citation><mixed-citation xml:lang="en">Bakris G, Gradman A, Reif M et al. Antihypertensive efficacy of candesartan in comparison to losartan: the CALM study. J Clin Hypertens (Greenwich) 2001; 3: 16-21.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Farsang C, Kawecka-Jjasziz K, Langan J et al. For the Multicentre Study Group. Antihypertensive effects and tolerability of candesartan cilexetil alone and in combination with amlodipine. Clin Drug Invest 2001; 2: 17-23.</mixed-citation><mixed-citation xml:lang="en">Farsang C, Kawecka-Jjasziz K, Langan J et al. For the Multicentre Study Group. Antihypertensive effects and tolerability of candesartan cilexetil alone and in combination with amlodipine. Clin Drug Invest 2001; 2: 17-23.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Mimran A, Aifaro V. Candesartan: nephroprotective effects and treatment of diabetic nephropathy. Drugs Today 2003; 39 (6): 439-50.</mixed-citation><mixed-citation xml:lang="en">Mimran A, Aifaro V. Candesartan: nephroprotective effects and treatment of diabetic nephropathy. Drugs Today 2003; 39 (6): 439-50.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Mitsunami K, Inoue S, Maeda K et al. Three-month effects of candesartan cilexetil, an angiotensin II type 1 (AT1) receptor antagonist, on left ventricular mass and hemodynamics in patients with essential hypertension. Cardiovasc Drugs Ther 1998; 12: 469-74.</mixed-citation><mixed-citation xml:lang="en">Mitsunami K, Inoue S, Maeda K et al. Three-month effects of candesartan cilexetil, an angiotensin II type 1 (AT1) receptor antagonist, on left ventricular mass and hemodynamics in patients with essential hypertension. Cardiovasc Drugs Ther 1998; 12: 469-74.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Блинова Е.В., Сахнова Т.А., Саидова М.А. и др. Информативность показателей ортогональной электрокардиограммы в диагностике гипертрофии левого желудочка. Тер. 2007; 4: 15-8.</mixed-citation><mixed-citation xml:lang="en">Блинова Е.В., Сахнова Т.А., Саидова М.А. и др. Информативность показателей ортогональной электрокардиограммы в диагностике гипертрофии левого желудочка. Тер. 2007; 4: 15-8.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Meredith P. Clinical comparative trials of angiotensine II type 1 (AT1) - receptor blockers. Blood Press 2001; 10 (Suppl. 3): 11-7.</mixed-citation><mixed-citation xml:lang="en">Meredith P. Clinical comparative trials of angiotensine II type 1 (AT1) - receptor blockers. Blood Press 2001; 10 (Suppl. 3): 11-7.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Fridman K, Wysoky M, Friberg P et al. A comparison of the inhibitory effects of candesartan cilexetil, losartan and valsartan on the response to angiotensin II in hypertensive patients. Am J Hypertens 1999; 12: 135A.</mixed-citation><mixed-citation xml:lang="en">Fridman K, Wysoky M, Friberg P et al. A comparison of the inhibitory effects of candesartan cilexetil, losartan and valsartan on the response to angiotensin II in hypertensive patients. Am J Hypertens 1999; 12: 135A.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Zanchetti A, Omboni S, on behalf of the Italian Candesartan Study Group. Comparison of candesartan versus enalapril in essential hypertension. Am J Hypertens 2001; 14: 129-34.</mixed-citation><mixed-citation xml:lang="en">Zanchetti A, Omboni S, on behalf of the Italian Candesartan Study Group. Comparison of candesartan versus enalapril in essential hypertension. Am J Hypertens 2001; 14: 129-34.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Parving HH, Lehnert H, Brohner-Mortensen J et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001; 345: 870-8.</mixed-citation><mixed-citation xml:lang="en">Parving HH, Lehnert H, Brohner-Mortensen J et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001; 345: 870-8.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Mogensen CE, Neldam S, Tikkanen I et al. Randomised controlled trial on dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: The candesartan and lisinopril microalbuminuria (CALM) study. BMJ 2000; 321: 1440-4.</mixed-citation><mixed-citation xml:lang="en">Mogensen CE, Neldam S, Tikkanen I et al. Randomised controlled trial on dual blockade of renin-angiotensin system in patients with hypertension, microalbuminuria, and non-insulin dependent diabetes: The candesartan and lisinopril microalbuminuria (CALM) study. BMJ 2000; 321: 1440-4.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Wheeldon N, Viberti G, for the MARVAL Trial. Microalbuminuria reduction with valsartan, Am J Hypertens 2001; 14: 2A.</mixed-citation><mixed-citation xml:lang="en">Wheeldon N, Viberti G, for the MARVAL Trial. Microalbuminuria reduction with valsartan, Am J Hypertens 2001; 14: 2A.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Rossing K, Christensen PK, Hansen BV et al. Optimal dose of candesartan for renoprotection in type 2 diabetic patients with nephropathy. Diabetic Care 2003; 26: 150-5.</mixed-citation><mixed-citation xml:lang="en">Rossing K, Christensen PK, Hansen BV et al. Optimal dose of candesartan for renoprotection in type 2 diabetic patients with nephropathy. Diabetic Care 2003; 26: 150-5.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kurokawa K, Abe K, Saruta T et al. Antiproteinuric effect of candesartan cilexetil in patients with chronic glomerulonephritis. J Ren Angiotens Aldoster Syst 2002; 3 (3): 167-75.</mixed-citation><mixed-citation xml:lang="en">Kurokawa K, Abe K, Saruta T et al. Antiproteinuric effect of candesartan cilexetil in patients with chronic glomerulonephritis. J Ren Angiotens Aldoster Syst 2002; 3 (3): 167-75.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Brenner BM, Cooper ME, de Zeeuw D et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-9.</mixed-citation><mixed-citation xml:lang="en">Brenner BM, Cooper ME, de Zeeuw D et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-9.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensine-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-60.</mixed-citation><mixed-citation xml:lang="en">Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensine-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-60.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Gansevoort RT, de Zeeuw D, de Long PE. Is the antiproteinuric effect of ACE inhibition mediated by interference in the renin-angiotensin system? Kidney Int 1994; 45: 861-7.</mixed-citation><mixed-citation xml:lang="en">Gansevoort RT, de Zeeuw D, de Long PE. Is the antiproteinuric effect of ACE inhibition mediated by interference in the renin-angiotensin system? Kidney Int 1994; 45: 861-7.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Andersen S, Jacobsen P, Tarnow L et al. Time course of the antiproteinuric and antihypertensive effect of Losartan in diabetic nephropathy. Nephrol Dial Transplant 2001; 16: 771-5.</mixed-citation><mixed-citation xml:lang="en">Andersen S, Jacobsen P, Tarnow L et al. Time course of the antiproteinuric and antihypertensive effect of Losartan in diabetic nephropathy. Nephrol Dial Transplant 2001; 16: 771-5.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Apperloo AJ, de Zeeuw D, de Long PE. Short-term antiproteinuric response to antihypertensive treatment predicts long-term GFR decline in patients with non-diabetic renal disease. Kidney Int 1994; 45 (Suppl. 45): S174-8.</mixed-citation><mixed-citation xml:lang="en">Apperloo AJ, de Zeeuw D, de Long PE. Short-term antiproteinuric response to antihypertensive treatment predicts long-term GFR decline in patients with non-diabetic renal disease. Kidney Int 1994; 45 (Suppl. 45): S174-8.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">de Jong PE, Navis Gj, de Zeeuw D. Renoprotective therapy: titration aganist urinary protein excretion. Lancet 1999; 354: 352-3.</mixed-citation><mixed-citation xml:lang="en">de Jong PE, Navis Gj, de Zeeuw D. Renoprotective therapy: titration aganist urinary protein excretion. Lancet 1999; 354: 352-3.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Rossing P, Hommel E, Smidt UM et al. Reduction in albuminuria predicts diminished progression in diabetic nephropathy. Kidney Int 45 1994; (Suppl. 45): S145-9.</mixed-citation><mixed-citation xml:lang="en">Rossing P, Hommel E, Smidt UM et al. Reduction in albuminuria predicts diminished progression in diabetic nephropathy. Kidney Int 45 1994; (Suppl. 45): S145-9.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Rossing P, Hommel E, Smidt UM et al. Reduction in albuminuria predicts a beneficial effects on diminishing the progression of human diabetic nephropathy during antihypertensive treatment. Diabetologia 1994; 37: 511-6.</mixed-citation><mixed-citation xml:lang="en">Rossing P, Hommel E, Smidt UM et al. Reduction in albuminuria predicts a beneficial effects on diminishing the progression of human diabetic nephropathy during antihypertensive treatment. Diabetologia 1994; 37: 511-6.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Gisen Group. Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, nondiabetic nephropathy. Lancet 1997; 349: 1857-63.</mixed-citation><mixed-citation xml:lang="en">Gisen Group. Randomised placebo-controlled trial of effect of ramipril on decline in glomerular filtration rate and risk of terminal renal failure in proteinuric, nondiabetic nephropathy. Lancet 1997; 349: 1857-63.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
