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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-190</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTICLES</subject></subj-group></article-categories><title-group><article-title>Синдром обструктивного апноэ во время сна. Механизмы возникновения. Клиническое значение. Связь с сердечно-сосудистыми заболеваниями. Принципы лечения</article-title><trans-title-group xml:lang="en"><trans-title>Obstructive sleep apnea syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Литвин</surname><given-names>А. Ю.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чазова</surname><given-names>И. Е.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Litvin</surname><given-names>A. Y.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>Chazova</surname><given-names>I. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГУ РКНПК Федерального агентства по высокотехнологичной медицинской помощи, Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>6</volume><issue>1</issue><fpage>32</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Литвин А.Ю., Чазова И.Е., Litvin A.Y., Chazova I.E., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Литвин А.Ю., Чазова И.Е., Litvin A.Y., Chazova I.E.</copyright-holder><copyright-holder xml:lang="en">Литвин А.Ю., Чазова И.Е., Litvin A.Y., Chazova I.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/190">https://www.syst-hypertension.ru/jour/article/view/190</self-uri><abstract><p>В статье подробно описаны основные механизмы возникновения синдрома обструктивного апноэ во время сна
(СОАС). На основании крупных популяционных рандомизированных исследований в этой области показана
значимость и распространенность нарушений дыхания во время сна обструктивного характера и обосновывается их
клиническое значение в практике врача - терапевта и кардиолога. По данным многочисленных литературных
источников продемонстрированы особенности взаимосвязи СОАС и сердечно-сосудистых заболеваний, а также
приводятся основные подходы и методы лечения на современном этапе.</p></abstract><trans-abstract xml:lang="en"><p>The paper describes the major mechanisms of occurrence of obstructive sleep apnea syndrome (OSAS). Large populationbased
randomized studies in this area show the importance and prevalence of obstructive sleep respiratory disorders and provide
evidence for their clinical significance in the practice of a therapist and cardiologist. Multiple references demonstrate the
specific features of an association of OSAS with cardiovascular diseases, as well as major treatment approaches and methods
at the present stage are given. Key words: obstructive sleep apnea syndrome, pathogenesis, epidemiology, diagnosis, clinical picture, treatment, cardiovascular
diseases</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром обструктивного апноэ во время сна</kwd><kwd>патогенез</kwd><kwd>эпидемиология</kwd><kwd>диагностика</kwd><kwd>клиника</kwd><kwd>лечение</kwd><kwd>заболевания сердечно-сосудистой системы</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Gastaut H, Tassarini C, Duron B. Etudes polygraphiques des manifestations episodiques (hypnique et respiratoire) du syndrome de Pickwick. Rev Neurol 1965; 112: 568-79.</mixed-citation><mixed-citation xml:lang="en">Gastaut H, Tassarini C, Duron B. Etudes polygraphiques des manifestations episodiques (hypnique et respiratoire) du syndrome de Pickwick. Rev Neurol 1965; 112: 568-79.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Yung R, Kuhlo W. 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