systhiperСистемные гипертензииSystemic Hypertension2075-082X2542-2189LLC «ИнтерМедсервис»systhiper-192Research ArticleСТАТЬИARTICLESÌåòàáîëè÷åñêèé ñèíäðîìMetabolic syndromeМычкаВ. Б.noemail@neicon.ruЧазоваИ. Е.noemail@neicon.ruMychkaV. B.noemail@neicon.ruChazovaI. E.noemail@neicon.ruОтдел системных гипертензий Института клинической кардиологии им. А.Л.Мясникова, ФГУ Российский кардиологический научно-производственный комплекс Росмедтехнологий, МоскваRussian Federation200923122022615053Copyright © Мычка В.Б., Чазова И.Е., Mychka V.B., Chazova I.E., 20222022Мычка В.Б., Чазова И.Е., Mychka V.B., Chazova I.E.Мычка В.Б., Чазова И.Е., Mychka V.B., Chazova I.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.syst-hypertension.ru/jour/article/view/192артериальная гипертензияметаболический синдромarterial hypertensionmetabolic syndromeReferencesReaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607.Reaven GM. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607.Kaplan NM. The deadly quartet: upper-body obesity, glucose intolerance, hypertriglyceridemia and hypertension. Arch Intern Med 1989; 149: 1514-1520.Kaplan NM. The deadly quartet: upper-body obesity, glucose intolerance, hypertriglyceridemia and hypertension. Arch Intern Med 1989; 149: 1514-1520.Bjorntop P. "Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes. Aterosclerosis 1990; 10: 493-6.Bjorntop P. "Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes. Aterosclerosis 1990; 10: 493-6.Julius S, Gudbrandsson T, Jamerson K et al. The hemodynamic link between insulin resistance and hypertension. J Hypertens 1991; 9: 983-6.Julius S, Gudbrandsson T, Jamerson K et al. The hemodynamic link between insulin resistance and hypertension. J Hypertens 1991; 9: 983-6.Hone J, Accili D, Al-Gazali LI et al. Homozygosity for a new mutation (ILe - Met) in the insulin receptor gene in five sibs with familial insulin resistance. J Med Genet 1994; 31: 715-6.Hone J, Accili D, Al-Gazali LI et al. Homozygosity for a new mutation (ILe - Met) in the insulin receptor gene in five sibs with familial insulin resistance. J Med Genet 1994; 31: 715-6.Widen E, Lehto M, Kannen T et al. Association of a polymorphism in the b3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. New Engl J Med 1995; 333: 348-51.Widen E, Lehto M, Kannen T et al. Association of a polymorphism in the b3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. New Engl J Med 1995; 333: 348-51.Neel JM. Diabetes mellitus: a thrifty genotype rendered detrimental by "progress"? Am J Hum Genet 1962; 14(2): 353-62.Neel JM. Diabetes mellitus: a thrifty genotype rendered detrimental by "progress"? Am J Hum Genet 1962; 14(2): 353-62.Piatti PM, Monti LD et al. Forearm insulin-and-non-insulin mediated glucose uptake and muscle metabolism in man: role of free fatty acids and blood glucose levels. Metab Clin Exp 1991; 40: 926-33.Piatti PM, Monti LD et al. Forearm insulin-and-non-insulin mediated glucose uptake and muscle metabolism in man: role of free fatty acids and blood glucose levels. Metab Clin Exp 1991; 40: 926-33.Evans DJ, Murray R, Kisselbah AH. Relationship between skeletal muscle insulin resistance, insulin mediated glucose disposal, and insulin binding. Effects of obesity and body fat topography. J Clin Invest 1984; 74: 74(4): 1515-25.Evans DJ, Murray R, Kisselbah AH. Relationship between skeletal muscle insulin resistance, insulin mediated glucose disposal, and insulin binding. Effects of obesity and body fat topography. J Clin Invest 1984; 74: 74(4): 1515-25.Keltikangas-Jarvinen L. Vital exhauston, anger expression, pituatry and adrenocortical hormones. Implications for the insulin resistance syndrime: Atherosclerosis, Thrombosis and Vascular Biology 1996; 16: 273-88.Keltikangas-Jarvinen L. Vital exhauston, anger expression, pituatry and adrenocortical hormones. Implications for the insulin resistance syndrime: Atherosclerosis, Thrombosis and Vascular Biology 1996; 16: 273-88.Uysal KT, Wiesbrock SM, Marino MW et al. Protection from obecity - induced insulin resistance in mice. Lacking TNF-alpha function. Nature 1997; 389: 610-4.Uysal KT, Wiesbrock SM, Marino MW et al. Protection from obecity - induced insulin resistance in mice. Lacking TNF-alpha function. Nature 1997; 389: 610-4.Muller G, Ertl J, Gerl M, Preibisch G. Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J Biol Chem 1997; 272: 10585-93.Muller G, Ertl J, Gerl M, Preibisch G. Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J Biol Chem 1997; 272: 10585-93.Kern PA, Saghizadeh M, OKern PA, Saghizadeh M, O
The authors declare that there are no conflicts of interest present.