systhiperСистемные гипертензииSystemic Hypertension2075-082X2542-2189LLC «ИнтерМедсервис»systhiper-205Research ArticleСТАТЬИARTICLESАтеросклеротический стеноз почечных артерий у больных сахарным диабетом 2-го типа и артериальной гипертензиейAtherosclerotic stenos of renal arteries at patients with diabetes mellitus and arterial hypertension.ФоминВ. В.noemail@neicon.ruМоисеевС. В.noemail@neicon.ruШвецовМ. Ю.noemail@neicon.ruМухинН. А.noemail@neicon.ruМосковская медицинская академия им. И.М.СеченоваRussian Federation200923122022632832Copyright © Фомин В.В., Моисеев С.В., Швецов М.Ю., Мухин Н.А., 20222022Фомин В.В., Моисеев С.В., Швецов М.Ю., Мухин Н.А.Фомин В.В., Моисеев С.В., Швецов М.Ю., Мухин Н.А.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.syst-hypertension.ru/jour/article/view/205

Обсуждаются проблемы диагностики и лечения ишемической болезни почек (атеросклеротический стеноз почечных арте- рий) у пациентов с сахарным диабетом типа 2.

Problems of diagnostics and treatment of ischemic renal disease (atherosclerotic stenosis of renal arteries) at patients with diabetes mellitus are discussed.

реноваскулярная артериальная гипертензиясахарный диабетReferencesMourad JJ, Le Jeune S. Blood pressure control, risk factors and cardiovascular prognosis in patients with diabetes: 30 years of progress. J Hypertens Suppl 2008; 26 (3): S7-13.Mourad JJ, Le Jeune S. Blood pressure control, risk factors and cardiovascular prognosis in patients with diabetes: 30 years of progress. J Hypertens Suppl 2008; 26 (3): S7-13.Ritz E, Orth SR. Nephropathy in patients with type 2 diabetes mellitus. N Engl J Med 1999; 341: 1127-33.Ritz E, Orth SR. Nephropathy in patients with type 2 diabetes mellitus. N Engl J Med 1999; 341: 1127-33.Mogensen CE. The kidney in diabetes: how to control renal and related cardiovascular complications. Am J Kidney Dis 2001; 37: S2-S6.Mogensen CE. The kidney in diabetes: how to control renal and related cardiovascular complications. Am J Kidney Dis 2001; 37: S2-S6.Дедов И.И., Шестакова М.В. Диабетическая нефропатия. М.: Универсум паблишинг, 2000.Дедов И.И., Шестакова М.В. Диабетическая нефропатия. М.: Универсум паблишинг, 2000.Yokoyama H, Okudaira M, Otani T et al. Higher incidence of diabetic nephropathy in type 2 than in type 1 diabetes in early-onset diabetes in Japan. Kidney Int 2000; 58 (1): 302-11.Yokoyama H, Okudaira M, Otani T et al. Higher incidence of diabetic nephropathy in type 2 than in type 1 diabetes in early-onset diabetes in Japan. Kidney Int 2000; 58 (1): 302-11.Harvey JN. Trends in the prevalence of diabetic nephropathy in type 1 and type 2 diabetes. Curr Opin Nephrol Hypertens 2003; 12 (3): 317-22.Harvey JN. Trends in the prevalence of diabetic nephropathy in type 1 and type 2 diabetes. Curr Opin Nephrol Hypertens 2003; 12 (3): 317-22.Оганов Р.Г., Лепахин В.К., Фитилев С.Б. и др. Качество профилактики и лечения сердечно-сосудистых заболеваний и их осложнений у больных сахарным диабетом 2 типа в амбулаторных условиях. Кардиоваск. тер. и проф. 2008; 7 (7): 9-14.Оганов Р.Г., Лепахин В.К., Фитилев С.Б. и др. Качество профилактики и лечения сердечно-сосудистых заболеваний и их осложнений у больных сахарным диабетом 2 типа в амбулаторных условиях. Кардиоваск. тер. и проф. 2008; 7 (7): 9-14.Lippert J, Ritz E, Schwarzbeck A, Schneider P. The rising tide of endstage renal failure from diabetic nephropathy type II - an epidemiological analysis. Nephrol Dial Transplant 1995; 10 (4): 462-7.Lippert J, Ritz E, Schwarzbeck A, Schneider P. The rising tide of endstage renal failure from diabetic nephropathy type II - an epidemiological analysis. Nephrol Dial Transplant 1995; 10 (4): 462-7.Dzielinska Z, Januszewicz A, Demkow M et al. Cardiovascular risk factors in hypertensive patients with coronary artery disease and coexisting renal artery stenosis. J Hypertens 2007; 25 (3): 663-70.Dzielinska Z, Januszewicz A, Demkow M et al. Cardiovascular risk factors in hypertensive patients with coronary artery disease and coexisting renal artery stenosis. J Hypertens 2007; 25 (3): 663-70.Alcasar JM, Marin R, Gomez-Campdera F et al. Clinical charasteristics of ischaemic renal disease. Nephrol Dial Transplant 2001; 16 (Suppl. 1): 74-7.Alcasar JM, Marin R, Gomez-Campdera F et al. Clinical charasteristics of ischaemic renal disease. Nephrol Dial Transplant 2001; 16 (Suppl. 1): 74-7.Sawicki PT, Kaiser S, Heinemann L et al. Prevalence of renal artery stenosis in diabetes mellitus - an autopsy study. J Intern Med 1991; 229 (6): 489-92.Sawicki PT, Kaiser S, Heinemann L et al. Prevalence of renal artery stenosis in diabetes mellitus - an autopsy study. J Intern Med 1991; 229 (6): 489-92.CourrПges JP, Bacha J, Aboud E. Prevalence and profile of renovascular disease in type II diabetic patients with severe hypertension. Arch Mal Coeur Vaiss 1997; 90 (8): 1059-63.CourrПges JP, Bacha J, Aboud E. Prevalence and profile of renovascular disease in type II diabetic patients with severe hypertension. Arch Mal Coeur Vaiss 1997; 90 (8): 1059-63.Courreges JP, Bacha J, Aboud E, Pradier P. Prevalence of renal artery stenosis in type 2 diabetes. Diabetes Metab 2000; 26 (Suppl. 4): 90-6.Courreges JP, Bacha J, Aboud E, Pradier P. Prevalence of renal artery stenosis in type 2 diabetes. Diabetes Metab 2000; 26 (Suppl. 4): 90-6.Valabhji J, Robinson S, Poulter C et al. Prevalence of renal artery stenosis in subjects with type 2 diabetes and coexistent hypertension. Diabetes Care 2000; 23: 539-43.Valabhji J, Robinson S, Poulter C et al. Prevalence of renal artery stenosis in subjects with type 2 diabetes and coexistent hypertension. Diabetes Care 2000; 23: 539-43.Kuroda S, Nishida N, Uzu T et al. Prevalence if renal artery stenosis in autopsy patients with stroke. Stroke 2000; 31: 61-5.Kuroda S, Nishida N, Uzu T et al. Prevalence if renal artery stenosis in autopsy patients with stroke. Stroke 2000; 31: 61-5.Horita Y, Tadokoro M, Taura K et al. Relationship between carotid artery intima-media thickness and atherosclerotic renal artery stenosis in type 2 diabetes with hypertension. Kidney Blood Press Res 2002; 25: 255-9.Horita Y, Tadokoro M, Taura K et al. Relationship between carotid artery intima-media thickness and atherosclerotic renal artery stenosis in type 2 diabetes with hypertension. Kidney Blood Press Res 2002; 25: 255-9.Kuczera P, Wloszczynska E, Adamczak M et al. Frequency of renal artery stenosis and variants of renal vascularization in hypertensive patients: analysis of 1550 angiographies in one centre. J Hum Hypertens 2009; 23 (6): 396-401.Kuczera P, Wloszczynska E, Adamczak M et al. Frequency of renal artery stenosis and variants of renal vascularization in hypertensive patients: analysis of 1550 angiographies in one centre. J Hum Hypertens 2009; 23 (6): 396-401.Horita Y, Tadokoro M, Taura K et al. Relationship between carotid artery intima-media thickness and atherosclerotic renal artery stenosis in type 2 diabetes with hypertension. Kidney Blood Press Res 2002; 25 (4): 255-9.Horita Y, Tadokoro M, Taura K et al. Relationship between carotid artery intima-media thickness and atherosclerotic renal artery stenosis in type 2 diabetes with hypertension. Kidney Blood Press Res 2002; 25 (4): 255-9.Vachharajani TJ, Dacie JE, Yaqoob MM et al. Detection of occult renovascular disease in unexplained chronic kidney disease. Int Urol Nephrol 2005; 37 (4): 793-6.Vachharajani TJ, Dacie JE, Yaqoob MM et al. Detection of occult renovascular disease in unexplained chronic kidney disease. Int Urol Nephrol 2005; 37 (4): 793-6.Фомин В.В. Ишемическая болезнь почек: клиническая картина, патогенез, тактика ведения. Автореф. дис. ... докт. мед. наук. М., 2008.Фомин В.В. Ишемическая болезнь почек: клиническая картина, патогенез, тактика ведения. Автореф. дис. ... докт. мед. наук. М., 2008.Domrongkitchaiporn S, Sritara P, Kitiyakara C et al. Risk factors for development of decreased kidney function in a southeast Asian population: a 12-year cohort study. J Am Soc Nephrol 2005; 16: 791-9.Domrongkitchaiporn S, Sritara P, Kitiyakara C et al. Risk factors for development of decreased kidney function in a southeast Asian population: a 12-year cohort study. J Am Soc Nephrol 2005; 16: 791-9.Stehouwer CD. Endothelial dysfunction in diabetic nephropathy: state of art and potential significance for non-diabetic renal disease. Nephrol Dial Transplant 2004; 19: 778-81.Stehouwer CD. Endothelial dysfunction in diabetic nephropathy: state of art and potential significance for non-diabetic renal disease. Nephrol Dial Transplant 2004; 19: 778-81.Шестакова М.В., Ярек-Мартынова И.Р., Иванишина Н.С. и др. Кардиоренальный синдром при сахарном диабете 1 типа: роль дисфункции эндотелия. Кардиология. 2005; 6: 35-41.Шестакова М.В., Ярек-Мартынова И.Р., Иванишина Н.С. и др. Кардиоренальный синдром при сахарном диабете 1 типа: роль дисфункции эндотелия. Кардиология. 2005; 6: 35-41.Гордеев А.В. Патология почек у больных сахарным диабетом 2 типа пожилого возраста. Автореф. дис. ... докт. мед. наук. М., 2002.Гордеев А.В. Патология почек у больных сахарным диабетом 2 типа пожилого возраста. Автореф. дис. ... докт. мед. наук. М., 2002.Фомин В.В., Моисеев С.В., Швецов М.Ю. и др. Ишемическая болезнь почек и сочетанные хронические нефропатии: клинические и прогностические особенности. Тер. арх. 2007; 6: 44-9.Фомин В.В., Моисеев С.В., Швецов М.Ю. и др. Ишемическая болезнь почек и сочетанные хронические нефропатии: клинические и прогностические особенности. Тер. арх. 2007; 6: 44-9.Myers DI, Poole LJ, Imam K et al. Renal artery stenosis by three-dimensional magnetic resonance angiography in type 2 diabetics with uncontrolled hypertension and chronic renal insufficiency: prevalence and effect on renal function. Am J Kidney Dis 2003; 41 (2): 351-9.Myers DI, Poole LJ, Imam K et al. Renal artery stenosis by three-dimensional magnetic resonance angiography in type 2 diabetics with uncontrolled hypertension and chronic renal insufficiency: prevalence and effect on renal function. Am J Kidney Dis 2003; 41 (2): 351-9.Ramos F, Kotliar C, Alvarez D et al. Renal function and outcome of PTRA and stenting for atherosclerotic renal artery stenosis. Kidney Int 2003; 63: 276-82.Ramos F, Kotliar C, Alvarez D et al. Renal function and outcome of PTRA and stenting for atherosclerotic renal artery stenosis. Kidney Int 2003; 63: 276-82.Alhadad A, Mattiasson I, Ivancev K et al. Predictors of long-term beneficial effects on blood pressure after percutaneous transluminal renal angioplasty in atherosclerotic renal artery stenosis. Int Angiol 2009; 28 (2): 106-12.Alhadad A, Mattiasson I, Ivancev K et al. Predictors of long-term beneficial effects on blood pressure after percutaneous transluminal renal angioplasty in atherosclerotic renal artery stenosis. Int Angiol 2009; 28 (2): 106-12.Mistry S, Ives N, Harding J et al. Angioplasty and STent for Renal Artery Lesions (ASTRAL trial): rationale, methods and results so far. J Hum Hypertens 2007; 21 (7): 511-5.Mistry S, Ives N, Harding J et al. Angioplasty and STent for Renal Artery Lesions (ASTRAL trial): rationale, methods and results so far. J Hum Hypertens 2007; 21 (7): 511-5.Kitazawa M, Tamamura H, Nakano S et al. Treatment of renovascular hypertension using stent implantation in an elderly patient with NIDDM. Intern Med 2000; 39: 464-7.Kitazawa M, Tamamura H, Nakano S et al. Treatment of renovascular hypertension using stent implantation in an elderly patient with NIDDM. Intern Med 2000; 39: 464-7.Zeller T, Muller C, Frank U et al. Stent angioplasty of severe atherosclerotic ostial renal artery stenosis in patients with diabetes mellitus and nephrosclerosis. Catheter Cardiovasc Interv 2003; 58: 510-5.Zeller T, Muller C, Frank U et al. Stent angioplasty of severe atherosclerotic ostial renal artery stenosis in patients with diabetes mellitus and nephrosclerosis. Catheter Cardiovasc Interv 2003; 58: 510-5.Silva JA, Potluri S, White CJ et al. Diabetes mellitus does not preclude stabilization or improvement of renal function after stent revascularization in patients with kidney insufficiency and renal artery stenosis. Catheter Cardiovasc Interv 2007; 69 (6): 902-7.Silva JA, Potluri S, White CJ et al. Diabetes mellitus does not preclude stabilization or improvement of renal function after stent revascularization in patients with kidney insufficiency and renal artery stenosis. Catheter Cardiovasc Interv 2007; 69 (6): 902-7.Davies MG, Saad WE, Peden EK et al. Implications of acute functional injury following percutaneous renal artery intervention. Ann Vasc Surg 2008; 22 (6): 783-9.Davies MG, Saad WE, Peden EK et al. Implications of acute functional injury following percutaneous renal artery intervention. Ann Vasc Surg 2008; 22 (6): 783-9.Toprak O, Cirit M. Risk factors for contrast-induced nephropathy. Kidney Blood Press Res 2006; 29 (2): 84-93.Toprak O, Cirit M. Risk factors for contrast-induced nephropathy. Kidney Blood Press Res 2006; 29 (2): 84-93.Vignali C, Bargellini I, Lazzereschi M et al. Predictive factors of in-stent restenosis in renal artery stenting: a retrospective analysis. Cardiovasc Intervent Radiol 2005; 28 (3): 296-302.Vignali C, Bargellini I, Lazzereschi M et al. Predictive factors of in-stent restenosis in renal artery stenting: a retrospective analysis. Cardiovasc Intervent Radiol 2005; 28 (3): 296-302.Shammas NW, Kapalis MJ, Dippel EJ et al. Clinical and angiographic predictors of restenosis following renal artery stenting. J Invasive Cardiol 2004; 16: 10-3.Shammas NW, Kapalis MJ, Dippel EJ et al. Clinical and angiographic predictors of restenosis following renal artery stenting. J Invasive Cardiol 2004; 16: 10-3.Symonides B, Januszewicz A, Rowinski O et al. Plasma fibrinogen as a risk factor for restenosis after percutaneous transluminal renal angioplasty in patients with atherosclerotic renal artery stenosis. J Cardiovasc Risk 1999; 6 (4): 269-72.Symonides B, Januszewicz A, Rowinski O et al. Plasma fibrinogen as a risk factor for restenosis after percutaneous transluminal renal angioplasty in patients with atherosclerotic renal artery stenosis. J Cardiovasc Risk 1999; 6 (4): 269-72.Silva JA. Evaluation and approach to treatment of renal artery stenosis in patients with diabetic nephropathy. Curr Diab Rep 2008; 8 (6): 494-8.Silva JA. Evaluation and approach to treatment of renal artery stenosis in patients with diabetic nephropathy. Curr Diab Rep 2008; 8 (6): 494-8.Rundback J. Renal revascularization in diabetics: few facts, firm convictions, forward momentum. Catheter Cardiovasc Interv 2007; 69 (6): 908-9.Rundback J. Renal revascularization in diabetics: few facts, firm convictions, forward momentum. Catheter Cardiovasc Interv 2007; 69 (6): 908-9.Российское медицинское общество по артериальной гипертонии - Всероссийское научное общество кардиологов. Диагностика и лечение артериальной гипертензии. Российские рекомендации (3-й пересмотр). М., 2008.Российское медицинское общество по артериальной гипертонии - Всероссийское научное общество кардиологов. Диагностика и лечение артериальной гипертензии. Российские рекомендации (3-й пересмотр). М., 2008.Staessen JA, Li Y, Richart T. Oral renin inhibitors. Lancet 2006; 368: 1449-56.Staessen JA, Li Y, Richart T. Oral renin inhibitors. Lancet 2006; 368: 1449-56.

The authors declare that there are no conflicts of interest present.