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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-285</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTICLES</subject></subj-group></article-categories><title-group><article-title>Новые широко обсуждаемые клинически значимые аспекты влияния b-блокаторов</article-title><trans-title-group xml:lang="en"><trans-title>The new widely discussed clinically significant aspects influence of β-blockers</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Арутюнов</surname><given-names>Г. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Arutyunov</surname><given-names>G. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГБОУ ВПО РНИМУ им. Н.И.Пирогова Минздрава РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>10</volume><issue>1</issue><fpage>80</fpage><lpage>87</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Арутюнов Г.П., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Арутюнов Г.П.</copyright-holder><copyright-holder xml:lang="en">Arutyunov G.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/285">https://www.syst-hypertension.ru/jour/article/view/285</self-uri><abstract><p>Назначение β-блокаторов в настоящее время представляет особый интерес. Существуют доводы за и против назначения этих препаратов. Так, с 2006-2008 гг. было опубликовано значительное количество работ, поставивших под сомнение роль β-блокаторов у пожилых больных артериальной гипертензией (АГ), в предотвращении развития хронической сердечной недостатончости (ХСН) у больных АГ, в повышении переносимости физических нагрузок у больных АГ. Однако в российских рекомендациях β-блокаторы сохранили свои показания и являются обязательными препаратами в лечении пациентов, страдающих АГ с высокой коморбидностью. В статье приводится анализ наиболее изученных β-блокаторов</p></abstract><trans-abstract xml:lang="en"><p>The use of b-blockers is of particular interest now. There are the pros and cons of prescribing these drugs. Thus, a considerable body of the papers that cast doubt on the role of b-blockers in elderly patients with arterial hypertension (AH) in preventing chronic heart failure and enhancing exercise endurance in patients with AH has been published since 2006–2008. However, the Russian guidelines have retained indications for the use of b-blockers that are indispensable drugs in the treatment of AH with high comorbidity. The paper analyzes the most studied b-blockers</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метопролола сукцинат</kwd></kwd-group><kwd-group xml:lang="en"><kwd>β-блокаторы</kwd><kwd>b-blockers</kwd><kwd>metoprolol succinate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bangalore S, Sawhney S, Messerli F.H. Relation of beta - blocker - induced heart rate lowering and cardioprotection in hypertension. 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