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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-311</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>Синдром обструктивного апноэ сна и дисфункция эндотелия</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галицин</surname><given-names>П. В.</given-names></name></name-alternatives><email xlink:type="simple">pgalicin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аксенова</surname><given-names>А. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елфимова</surname><given-names>Е. М.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ишанходжаева</surname><given-names>Г. Р.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балахонова</surname><given-names>Т. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Литвин</surname><given-names>А. Ю.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чазова</surname><given-names>И. Е.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБУ РКНПК Минздрава России, Москва</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>10</volume><issue>3</issue><fpage>85</fpage><lpage>91</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Галицин П.В., Аксенова А.В., Елфимова Е.М., Ишанходжаева Г.Р., Балахонова Т.В., Литвин А.Ю., Чазова И.Е., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Галицин П.В., Аксенова А.В., Елфимова Е.М., Ишанходжаева Г.Р., Балахонова Т.В., Литвин А.Ю., Чазова И.Е.</copyright-holder><copyright-holder xml:lang="en">Галицин П.В., Аксенова А.В., Елфимова Е.М., Ишанходжаева Г.Р., Балахонова Т.В., Литвин А.Ю., Чазова И.Е.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/311">https://www.syst-hypertension.ru/jour/article/view/311</self-uri><abstract><p>Статья посвящена вопросам взаимосвязи синдрома обструктивного апноэ сна (СОАС) и сердечно-сосудистых заболеваний. Более подробно описан вопрос взаимодействия дисфункции эндотелия (ДЭ) и СОАС. Обсуждены современные представления о механизмах развития артериальной гипертензии при СОАС. Приводятся как доказательные данные, так и мнения экспертов. Рассмотрены вопросы влияния постоянного положительного давления в дыхательных путях на ДЭ.</p></abstract><kwd-group xml:lang="ru"><kwd>синдром обструктивного апноэ сна</kwd><kwd>дисфункция эндотелия</kwd><kwd>артериальная гипертензия</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Malhotra A, White D.P. Obstructive sleep apnoea. Lancet 2002; 360: 237–45.</mixed-citation><mixed-citation xml:lang="en">Malhotra A, White D.P. Obstructive sleep apnoea. Lancet 2002; 360: 237–45.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bray G.A. Pathophysiology of obesity. 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