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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-334</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Место блокаторов рецепторов ангиотензина в антигипертензивной терапии</article-title><trans-title-group xml:lang="en"><trans-title>Place of angiotensin receptor blockers in antihypertensive therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартынов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Martynov</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Урлаева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Urlaeva</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акатова</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Akatova</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николин</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolin</surname><given-names>O. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГБОУ ВПО Московский государственный медико-стоматологический университет им. А.И.Евдокимова Минздрава России</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>11</volume><issue>1</issue><fpage>34</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мартынов А.И., Урлаева И.В., Акатова Е.В., Николин О.П., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Мартынов А.И., Урлаева И.В., Акатова Е.В., Николин О.П.</copyright-holder><copyright-holder xml:lang="en">Martynov A.I., Urlaeva I.V., Akatova E.V., Nikolin O.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/334">https://www.syst-hypertension.ru/jour/article/view/334</self-uri><abstract><p>Артериальная гипертензия занимает основное место среди сердечно-сосудистых заболеваний, являющихся основной причиной смерти и нетрудоспособности. На сегодняшний день основной группой препаратов для лечения артериальной гипертензии остаются ингибиторы ангиотензинпревращающего фермента (ИАПФ). По данным многочисленных исследований, блокаторы рецепторов ангиотензина II по своей эффективности равны ИАПФ, однако они имеют лучший профиль переносимости и обеспечивают более высокую приверженность терапии. Одним из высокоэффективных, хорошо изученных препаратов со значительной доказательной базой является ирбесартан.</p></abstract><trans-abstract xml:lang="en"><p>The arterial hypertension takes the basic place among the cardiovascular diseases which are a principal cause of death and invalidity. For today the basic group for treatment of an arterial hypertensia remain angiotensin-converting enzyme inhibitors (ACEi). However, according to numerous researches, angiotensin II receptor inhibitors by the efficiency are equal with ACEi, but have the best profile of shipping and provide higher adherence to therapy. One of highly effective, well studied, with considerable demonstrative base of preparations irbesartan.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>ренин-ангиотензиновая система</kwd><kwd>блокаторы рецепторов ангиотензина II</kwd><kwd>ирбесартан</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>renin-angiotenzin system</kwd><kwd>angiotensin II receptor inhibitors</kwd><kwd>irbesartan</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Диагностика и лечение артериальной гипертензии. Кардиоваск. терапия и профилактика. 2008; 7 (6). Прил. 2.</mixed-citation><mixed-citation xml:lang="en">Диагностика и лечение артериальной гипертензии. Кардиоваск. терапия и профилактика. 2008; 7 (6). 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