systhiperСистемные гипертензииSystemic Hypertension2075-082X2542-2189LLC «ИнтерМедсервис»systhiper-335Research ArticleМЕТАБОЛИЧЕСКИЕ НАРУШЕНИЯMETABOLIC DISTURBANCESРиск поражения органов-мишеней у больных артериальной гипертонией с разным числом компонентов метаболического синдромаRisk of target organ damage in patients with arterial hypertension and various numbers of metabolic syndrome componentsЖернаковаЮ. В.ZhernakovaYu. V.juli001@mail.ruШариповаГ. Х.SharipovaG. Kh.noemail@neicon.ruЧазоваИ. Е.ChazovaI. E.c34h@yandex.ruИнститут клинической кардиологии им. А.Л.Мясникова ФГБУ РКНПК Минздрава России, МоскваRussian Federation2014231220221114044Copyright © Жернакова Ю.В., Шарипова Г.Х., Чазова И.Е., 20222022Жернакова Ю.В., Шарипова Г.Х., Чазова И.Е.Zhernakova Y.V., Sharipova G.K., Chazova I.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.syst-hypertension.ru/jour/article/view/335

Метаболический синдром (МС) является одной из наиболее социально значимых и приоритетных проблем клинической медицины. Известно, что наличие МС способствует более раннему и выраженному поражению органов-мишеней у больных артериальной гипертонией (АГ). Однако связь числа одновременно встречающихся компонентов МС с поражением органов-мишеней, выделение отдельных компонентов МС, влияющих на выраженность поражения органов-мишеней, изучены недостаточно. В проведенной нами работе установлено, что с увеличением числа компонентов МС происходит рост частоты и выраженности поражения сердца, почек и сосудов, что сопровождается повышенным риском развития сердечно-сосудистых осложнений у больных с максимальным числом компонентов МС. Кроме того, выявлено, что относительный риск одновременного поражения сердца, почек и сосудов у больных АГ с МС помимо повышенного АД и абдоминального ожирения ассоциируется с увеличением уровня глюкозы натощак.

The metabolic syndrome is one of most socially significant and strategic problems of clinical medicine. It is known that metabolic syndrome promotes earlier and more expressed target organ damage in patients with arterial hypertension. However, correlation of the number of metabolic syndrome components with target organ damage, selection of metabolic syndrome components, influencing expressiveness on target organ damage, are studied insufficiently. In this study it is determined that with the elevating number of the metabolic syndrome components, the frequency and expressiveness of heart, kidney and vessel damage, accompanied by the increased risk of development of cardiovascular complications, increase in patients with the maximum number of the metabolic syndrome components. Moreover, it is revealed that the relative risk of simultaneous damage of heart, kidneys and vessels in patients with arterial hypertension and metabolic syndrome, apart from high blood pressure and abdominal obesity is associated with the increase of fasting glucose level.

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The authors declare that there are no conflicts of interest present.