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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-393</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>Еще раз о клинической эффективности и безопасности сартанов</article-title><trans-title-group xml:lang="en"><trans-title>Once again about the clinical efficacy and safety of sartans</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Минина</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Minina</surname><given-names>Ye. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хаджиева</surname><given-names>Б. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khadzhieva</surname><given-names>B. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУ Поликлиника №3 Управления делами Президента РФ, Москва<country>Россия</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ГБОУ ВПО Первый московский государственный медицинский университет им. И.М.Сеченова Минздрава России<country>Россия</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>11</volume><issue>4</issue><fpage>84</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Минина Е.С., Хаджиева Б.Р., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Минина Е.С., Хаджиева Б.Р.</copyright-holder><copyright-holder xml:lang="en">Minina Y.S., Khadzhieva B.R.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/393">https://www.syst-hypertension.ru/jour/article/view/393</self-uri><abstract><p>Сартаны в настоящее время - наиболее безопасный и эффективный класс гипотензивных препаратов. У пациентов, страдающих артериальной гипертензией (АГ), наибольшая приверженность лечению наблюдается именно при назначении сартанов. Их эффективность определяет сила связи с рецептором ангиотензина II 1-го типа. Наиболее сильна связь с рецептором у кандесартана и азилсартана. При этом кандесартан по сравнению с азилсартаном имеет широкие показания. У азилсартана показанием служит АГ. Данные сартаны освещены с точки зрения эффективности и безопасности.</p></abstract><trans-abstract xml:lang="en"><p>Sartans are safety and effective class of anti-hypertensives nowadays. Sartans are the most effective inpatients suffering from arterial hypertension. Their efficiency is determined by the association of Angiotensin II type 1 receptor. Candesartan and azilsartan are themost powerful and approved angiotensin receptor blockers. Candesartan in comparison with azilsartan has wide proposed spectrum of clinical use. Azilsartan is indicated for the treatment of arterial hypertension. In terms of efficiency and safety we showed these sartans.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сартаны</kwd><kwd>кандесартан</kwd><kwd>азилсартан</kwd><kwd>артериальная гипертензия</kwd><kwd>хроническая сердечная недостаточность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>sartans</kwd><kwd>candesartan</kwd><kwd>azilsartan</kwd><kwd>arterial hypertension</kwd><kwd>chronic heart failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Conlin P.R, Gerth W.C, Fox J et al. Four - year persistence patterns among patients initiating therapy with the angiotensin II receptor antagonist losartan versus other artihypertensive drug classes. Clin Ther 2001; 23 (12): 1999-2010.</mixed-citation><mixed-citation xml:lang="en">Conlin P.R, Gerth W.C, Fox J et al. 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