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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-404</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОНЕВРОЛОГИЯ / CARDIONEUROLOGY</subject></subj-group></article-categories><title-group><article-title>Значение выбора гипотензивной терапии в коррекции поражений головного мозга:от легких когнитивных нарушений до деменции</article-title><trans-title-group xml:lang="en"><trans-title>The meaning of hypertensive therapy choice in the correction of cerebral affection: from mild cognitive impairment to dementia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишкова</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Shishkova</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">veronika-1306@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ Центр патологии речи и нейрореабилитации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center for Speech Pathology and Neurorehabilitation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>12</volume><issue>1</issue><fpage>58</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шишкова В.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Шишкова В.Н.</copyright-holder><copyright-holder xml:lang="en">Shishkova V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/404">https://www.syst-hypertension.ru/jour/article/view/404</self-uri><abstract><p>Нарушения и болезни нервной системы занимают сегодня первое место среди причин инвалидности. Доля их в общей заболеваемости и инвалидизации растет, что вызвано глобальным ростом сосудистых заболеваний мозга - острых и хронических нарушений мозгового кровообращения. Клиническая картина хронических нарушений мозгового кровообращения, формируясь постепенно, включает в том числе и развитие когнитивных нарушений, вплоть до деменции. Плацдармом для их развития могут служить длительно существующие сердечно-сосудистые заболевания (ССЗ). Проблема формирования когнитивных нарушений у пациентов с ССЗ, особенно артериальной гипертензией (АГ), является актуальной, с учетом постоянного роста распространенности данной патологии в популяции. Возможность повлиять на состояние когнитивных функций у пациентов с АГ, используя традиционные антигипертензивные препараты - сартаны, в процессе достижения целевых значений артериального давления существует. Однако описаны дополнительные преимущества отдельных препаратов данной группы, таких как Микардис и Твинста, в коррекции развития нарушений когнитивных функций.</p></abstract><trans-abstract xml:lang="en"><p>Disorders and neuropathy are the leading cause of disability. Their partof total morbidity and disability is increasing due to the global growth of vascular diseases of the brain: the acute and the chronic disorders of cerebral circulation. The clinical characteristics of chronic disorders of cerebral circulation have been forming gradually, and include the development of cognitive impairments, up to dementia. The base for their development can serve thelong-term cardiovascular diseases (CVD). The problem of cognitive impairments in patients with CVD, particularly with arterial hypertension (AH), is a leading one, taking into consideration the fact that these disorders are continuing to grow in the population. There is a real possibility to impact on the cognitive functions condition in patients with AH, using traditional antihypertensive drugs such assartans to achieve the target blood pressure levels. However, there is the additional benefit of special drugs in this group, such as Micardis and Twynsta, in the correction of cognitive function disorders.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>когнитивные нарушения</kwd><kwd>артериальная гипертензия</kwd><kwd>телмисартан</kwd><kwd>амлодипин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cognitive impairment</kwd><kwd>arterial hypertension</kwd><kwd>telmisartan</kwd><kwd>amlodipine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Захаров В.В., Яхно Н.Н. Когнитивные расстройства в пожилом и старческом возрасте. Методическое пособие для врачей. 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