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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-433</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕТАБОЛИЧЕСКИЕ НАРУШЕНИЯ / METABOLIC DISTURBANCES</subject></subj-group></article-categories><title-group><article-title>Лечение артериальной гипертензии у пациентов с избыточной массой тела</article-title><trans-title-group xml:lang="en"><trans-title>Treatment of hypertension in overweight patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кукес</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kukes</surname><given-names>V. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аникин</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Anikin</surname><given-names>G. S.</given-names></name></name-alternatives><email xlink:type="simple">medi321@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреевская</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreevskaya</surname><given-names>E. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ашуркова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ashurkova</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБОУ ВПО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава России; ФГБУ Поликлиника №3 Управления делами Президента РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation; Out-Patient Clinic №3 of Administration of the President of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ Поликлиника №3 Управления делами Президента РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Out-Patient Clinic №3 of Administration of the President of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>12</volume><issue>3</issue><fpage>46</fpage><lpage>49</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кукес В.Г., Аникин Г.С., Андреевская Е.М., Ашуркова Е.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Кукес В.Г., Аникин Г.С., Андреевская Е.М., Ашуркова Е.А.</copyright-holder><copyright-holder xml:lang="en">Kukes V.G., Anikin G.S., Andreevskaya E.M., Ashurkova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/433">https://www.syst-hypertension.ru/jour/article/view/433</self-uri><abstract><p>При лечении артериальной гипертензии у пациентов с избыточной массой тела целью является не только нормализация артериального давления, но и улучшение показателей эндотелиальной функции, снижение инсулинорезистентности, нормализация показателей липидного обмена. Одни из препаратов, обладающие широкими терапевтическими возможностями и большой доказательной базой, - агонисты I1-имидазолиновых рецепторов, которые могут назначаться как в монотерапии, так и в составе комбинированной терапии лицам с избыточной массой тела.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the treatment of hypertension in patients with overweight is not only normalization of blood pressure, but also improvement of endothelial function, reduction of insulin resistance and lipid metabolism. Some of the drugs with a broad therapeutic spectrum and huge evidential base, - I1-imidazoline-receptor agonists can be applied in both monotherapy and as a part of the combined therapy in overweight patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>избыточная масса тела</kwd><kwd>моксонидин</kwd><kwd>Физиотенз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>overweight</kwd><kwd>moxonidine</kwd><kwd>Physiotens</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kotseva K et al. EUROASPIRE IV: A European Society of Cardiology survey on the lifestyle, risk factor and therapeutic management of coronary patients from 24 European countries. Eur J Prev Cardiol 2015.</mixed-citation><mixed-citation xml:lang="en">Kotseva K et al. 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