systhiperСистемные гипертензииSystemic Hypertension2075-082X2542-2189LLC «ИнтерМедсервис»systhiper-445Research ArticleКАРДИОПУЛЬМОНОЛОГИЯ / CARDIOPULMONOLOGYСопоставление векторкардиографических параметров со структурно-функциональным состоянием правого желудочка у пациентов с легочной гипертензиейComparison of vectorcardiographic parameters with structural-functional state of the right ventricle in patients with pulmonary hypertensionБлиноваЕ. В.BlinovaE. V.noemail@neicon.ruСахноваТ. А.SakhnovaT. A.tamara-sahnova@mail.ruСаидоваМ. А.SaidovaM. A.noemail@neicon.ruЛоскутоваА. С.LoskutovaA. S.noemail@neicon.ruРябыкинаГ. В.RyabykinaG. V.noemail@neicon.ruАрхиповаО. А.ArkhipovaO. A.noemail@neicon.ruМартынюкТ. В.MartynyukT. V.trukhiniv@mail.ruТруновВ. Г.TrunovV. G.noemail@neicon.ruАйдуЭ. А.AiduE. A.noemail@neicon.ruЧазоваИ. Е.ChazovaI. E.noemail@neicon.ruФГБУ Российский кардиологический научно-производственный комплекс Минздрава РоссииРоссияRussian Cardiological Scientific-Industrial Complex of the Ministry of Health of the Russian FederationRussian FederationФГБУН Институт проблем передачи информации им. А.А.Харкевича РАНРоссияA.A.Kharkevich Institute for Information Transmission Problems of RASRussian Federation2015231220221245760Copyright © Блинова Е.В., Сахнова Т.А., Саидова М.А., Лоскутова А.С., Рябыкина Г.В., Архипова О.А., Мартынюк Т.В., Трунов В.Г., Айду Э.А., Чазова И.Е., 20222022Блинова Е.В., Сахнова Т.А., Саидова М.А., Лоскутова А.С., Рябыкина Г.В., Архипова О.А., Мартынюк Т.В., Трунов В.Г., Айду Э.А., Чазова И.Е.Blinova E.V., Sakhnova T.A., Saidova M.A., Loskutova A.S., Ryabykina G.V., Arkhipova O.A., Martynyuk T.V., Trunov V.G., Aidu E.A., Chazova I.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.syst-hypertension.ru/jour/article/view/445

Изменения векторкардиографического желудочкового градиента (VG) у пациентов с легочной артериальной гипертензией (ЛАГ) являются показателем перегрузки правого желудочка (ПЖ) и могут использоваться для оценки ее тяжести. Целью исследования было оценить взаимосвязь векторкардиографических показателей VG и пространственный угол QRS-T с эхокардиографическими показателями структурно-функционального состояния ПЖ.У 30 пациентов с ЛАГ были оценены размеры ПЖ; амплитуда экскурсии фиброзного кольца трикуспидального клапана (TAPSE), относительное изменение площади ПЖ (FAC), систолическая скорость ПЖ (TDI-S’); продольная деформация (LS). VG и пространственный угол QRS-T рассчитывали с использованием ортогональных отведений, синтезированных из стандартной электрокардиографии.Пространственная компонента VG-Y имела умеренную отрицательную корреляцию с LS (r=-0,62; p <0,005); амплитуда VG и компоненты VG-Х и VG-Y - положительные корреляции с FAC (r от 0,50 до 0,65; р <0,005); амплитуда VG и компонента VG-Y - положительные корреляции с TDI-S’ (r 0,58 и 0,53; p <0,005), пространственный угол QRS-T - отрицательные корреляции с TAPSE (r=-0,59; p <0,005), FAC (r=-0,66; p <0,005) и TDI-S’ (r=-0,67); p <0,005.У лиц с тяжелой ЛАГ VG и пространственный угол QRS-T коррелируют не только с размерами ПЖ и давлением в легочной артерии, но и с параметрами систолической функции ПЖ.

Changes of the vectrocardiographic ventricular gradient (VG) in patients with pulmonary arterial hypertension (PAH) are indicative of right ventricular (RV) overload and may be used to assess its severity. The study aim was to evaluate interrelations between vectrocardiographic VG, spatial QRS-T angle and echocardiographic parameters of structural-functional state of the RV.The following parameters were assessed in 30 PAH patients: RV dimensions; tricuspid annular plane systolic excursion (TAPSE); RV fractional area change (FAC); RV peak systolic annular velocity (TDI-S’), and longitudinal strain (LS). VG and spatial QRS-T angle were calculated using the orthogonal leads derived from standard echocardiography.Spatial component VG-Y had moderate negative correlation with LS (r=-0.62; p <0.005); VG magnitude, VG-X and VG-Y had positive correlations with FAC (r from 0.50 to 0.65; p <0.005); VG magnitude and VG-Y had positive correlations with TDI-S’ (0.58 and 0.53; p <0.005); spatial QRS-T angle had negative correlation with TAPSE (r=-0.59; p <0.005), FAC (r=-0.66; p <0.005) and TDI-S’ (r=-0.67); p <0.005.In patients with severe PAH, VG and spatial QRS-T angle correlate not only with RV dimensions and pulmonary artery pressure, but with parameters of RV systolic function.

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The authors declare that there are no conflicts of interest present.