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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-449</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ / CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Предикторы прогрессирования фибрилляции предсердий у пациентов с артериальной гипертензией</article-title><trans-title-group xml:lang="en"><trans-title>Predictors of progression of atrial fibrillation in patients with arterial hypertension</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подзолков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Podzolkov</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарзиманова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarzimanova</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">tarzimanova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>13</volume><issue>1</issue><fpage>11</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Подзолков В.И., Тарзиманова А.И., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Подзолков В.И., Тарзиманова А.И.</copyright-holder><copyright-holder xml:lang="en">Podzolkov V.I., Tarzimanova A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/449">https://www.syst-hypertension.ru/jour/article/view/449</self-uri><abstract><p>В последнее время достигнуты определенные успехи в изучении естественного течения фибрилляции предсердий (ФП): от стадии, не имеющей клинических проявлений, до конечной стадии, представляющей собой необратимую аритмию, ассоциирующуюся с развитием серьезных сердечно-сосудистых осложнений. Прогрессия аритмии ухудшает клинический статус пациентов и их прогноз. Замедление прогрессии ФП следует рассматривать в качестве одной из приоритетных задач лечения данного нарушения сердечного ритма.Цель - изучить предикторы прогрессирования ФП у больных артериальной гипертензией (АГ).Материалы и методы. В исследование включены 136 пациентов с эссенциальной АГ и пароксизмами ФП. Проспективное наблюдение за больными проводилось с 2011 по 2015 г. Прогрессированием аритмии считали: увеличение частоты пароксизмов ФП; появление длительно персистирующих приступов или постоянной формы аритмии.Результаты нашей работы позволяют сделать вывод, что предикторами прогрессирования ФП у пациентов с АГ с сохраненной систолической функцией левого желудочка являются: дисфункция эндотелия, повышение жесткости сосудистой стенки, гипертрофия левого желудочка и увеличение размеров левого предсердия.</p></abstract><trans-abstract xml:lang="en"><p>Recently progress has been made in the study of the natural history of atrial fibrillation (AF) from the stage without clinical manifestations, to the final stage, represent an irreversible arrhythmia associated with the development of serious cardiovascular complications. The progression of the arrhythmia worsens the clinical status of patients and prognosis. Slowing down progression of AF should be considered as a priority treatment of this cardiac arrhythmia.Aim. The study the predictors of AF progression in patients with arterial hypertension.Materials and methods. The study included 136 patients with essential hypertension and paroxysms of AF. Prospective observation of the patients was carried out from 2011 to 2015. The progression of the arrhythmia was considered: increased frequency of paroxysms of AF; the emergence of long-term persistent attacks or permanent form of arrhythmia.The results of our work allow to conclude that the predictors of progression of AF in patients with hypertension and preserved systolic left ventricular function are: endothelial dysfunction, increased vascular wall stiffness, left ventricle hypertrophy and increased size of the left atrium.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>фибрилляция предсердий</kwd><kwd>предикторы прогрессирования</kwd><kwd>артериальная гипертензия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrial fibrillation</kwd><kwd>predictors of progression</kwd><kwd>arterial hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Канорский С.Г. 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