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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-454</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВОПРОСЫ ДИАГНОСТИКИ / QUESTIONS OF DIAGNOSTICS</subject></subj-group></article-categories><title-group><article-title>МикроРНК в диагностике хронической сердечной недостаточности: состояние проблемы и результаты пилотного исследования</article-title><trans-title-group xml:lang="en"><trans-title>MicroRNA in the diagnosis of chronic heart failure: state of the problem and the results of a pilot study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жиров</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhirov</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">izhirov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кочетов</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kochetov</surname><given-names>A. G.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Засеева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaseeva</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лянг</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Liang</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скворцов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Skvortsov</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абрамов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Abramov</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гимадиев</surname><given-names>Р. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Gimadiev</surname><given-names>R. R.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Масенко</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Masenko</surname><given-names>V. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Терещенко</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tereshchenko</surname><given-names>S. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт клинической кардиологии им. А.Л.Мясникова ФГБУ Российский кардиологический научно-производственный комплекс Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.L.Myasnikov Institute of Clinical Cardiology, Russian Cardiological Scientific-Industrial Complex of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт клинической кардиологии им. А.Л.Мясникова ФГБУ Российский кардиологический научно-производственный комплекс Минздрава России; ФГАОУ ВО Российский университет дружбы народов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.L.Myasnikov Institute of Clinical Cardiology, Russian Cardiological Scientific-Industrial Complex of the Ministry of Health of the Russian Federation; People’s Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО Российский университет дружбы народов</institution><country>Россия</country></aff><aff xml:lang="en"><institution>People’s Friendship University of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУЗ Научно-практический центр медицинской помощи детям с пороками развития черепно-лицевой области и врожденными заболеваниями нервной системы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Scientific and practical center of medical aid to children with congenital abnormality of craniofacial area and congenital diseases of the nervous system</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>13</volume><issue>1</issue><fpage>39</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жиров И.В., Кочетов А.Г., Засеева А.В., Лянг О.В., Скворцов А.А., Абрамов А.А., Гимадиев Р.Р., Масенко В.П., Терещенко С.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Жиров И.В., Кочетов А.Г., Засеева А.В., Лянг О.В., Скворцов А.А., Абрамов А.А., Гимадиев Р.Р., Масенко В.П., Терещенко С.Н.</copyright-holder><copyright-holder xml:lang="en">Zhirov I.V., Kochetov A.G., Zaseeva A.V., Liang O.V., Skvortsov A.A., Abramov A.A., Gimadiev R.R., Masenko V.P., Tereshchenko S.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/454">https://www.syst-hypertension.ru/jour/article/view/454</self-uri><abstract><p>В статье приводятся данные о классе некодирующих РНК - микроРНК, их роли в диагностике хронической сердечной недостаточности, а также результаты пилотного исследования.</p></abstract><trans-abstract xml:lang="en"><p>The article provides information about the class of non-coding RNA (microRNA), their role in the diagnosis of chronic heart failure and the results of a pilot study.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>микроРНК</kwd><kwd>экспрессия микроРНК</kwd><kwd>диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic heart failure</kwd><kwd>microRNA</kwd><kwd>microRNA expression</kwd><kwd>diagnostics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bartel D.P. 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