systhiperСистемные гипертензииSystemic Hypertension2075-082X2542-2189LLC «ИнтерМедсервис»systhiper-467Research ArticleМЕТАБОЛИЧЕСКИЕ НАРУШЕНИЯMETABOLIC DISTURBANCESНефропротекция у больных с метаболическим синдромом: подходы к назначению антигипертензивных препаратовNephroprotective in patients with metabolic syndrome: approaches to the appointment of antihypertensive drugsОстроумоваО. Д.OstroumovaO. D.ostroumova.olga@mail.ruЗыковаА. А.ZykovaA. A.alexandra-z@mail.ruМаксимовМ. Л.MaksimovM. L.maksim_maksimov@mail.ruГБОУ ВПО Московский государственный медико-стоматологический университет им. А.И.Евдокимова Минздрава России; ГБОУ ВПО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава РоссииРоссияA.I.Evdokimov Moscow State Medical and Dental University of the Ministry of Health of the Russian Federation; I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationRussian FederationГБОУ ВПО Московский государственный медико-стоматологический университет им. А.И.Евдокимова Минздрава РоссииРоссияA.I.Evdokimov Moscow State Medical and Dental University of the Ministry of Health of the Russian FederationRussian FederationГБОУ ВПО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава РоссииРоссияI.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationRussian Federation2016231220221327783Copyright © Остроумова О.Д., Зыкова А.А., Максимов М.Л., 20222022Остроумова О.Д., Зыкова А.А., Максимов М.Л.Ostroumova O.D., Zykova A.A., Maksimov M.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.syst-hypertension.ru/jour/article/view/467

В статье рассмотрены вопросы распространенности, диагностики и прогностической значимости поражения почек при метаболическом синдроме. Обсуждаются патогенетические механизмы развития и прогрессирования хронической болезни почек у лиц с ожирением. Приведены подходы к выбору антигипертензивных препаратов, рассмотрены преимущества и ограничения основных классов антигипертензивных лекарственных средств при лечении метаболического синдрома, артериальной гипертонии в сочетании с поражением почек.

In the article shows the questions of prevalence, diagnosis and prognostic significance of renal damage in metabolic syndrome. Discusses the pathogenetic mechanisms of development and progression of chronic kidney disease in individuals with obesity. Approaches to selection of antihypertensive drugs, advantages and limitations of the major classes of antihypertensive drugs in the treatment of metabolic syndrome, arterial hypertension combined with renal disease.

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The authors declare that there are no conflicts of interest present.