systhiperСистемные гипертензииSystemic Hypertension2075-082X2542-2189LLC «ИнтерМедсервис»systhiper-523Research ArticleСТАТЬИARTICLESРуководство по диагностике, профилактике и лечению сердечно-сосудистых осложнений противоопухолевой терапии. Части II-VClinical Manual for Diagnosis, Prevention and Treatment of Cardiovascular Complications of Cancer Therapy. Parts II-VЧазоваИ. Е.ChazovaI. Ye.noemail@neicon.ruТюляндинС. А.TyulyandinS. A.noemail@neicon.ruВиценяМ. В.VitseniaM. V.marinavitsenya@gmail.comПолтавскаяМ. Г.PoltavskayaM. G.noemail@neicon.ruГиляровМ. Ю.GilyarovM. Yu.noemail@neicon.ruМартынюкТ. В.MartynyukT. V.noemail@neicon.ruОвчинниковА. Г.OvchinnikovA. G.noemail@neicon.ruПанченкоЕ. П.PanchenkoE. P.noemail@neicon.ruФедоткинаЮ. А.FedotkinaYu. A.noemail@neicon.ruСтенинаМ. Б.SteninaM. B.noemail@neicon.ruТрофимоваО. П.TrophimovaO. P.noemail@neicon.ruАгеевФ. Т.AgeevF. T.noemail@neicon.ruФГБУ «НМИЦ кардиологии»РоссияA.L.Myasnikov Institute of Clinical Cardiology National Medical Research Center of Cardiology of the Ministry of Health of the Russian FederationRussian FederationФГБУ «НМИЦ онкологии им. Н.Н.Блохина»РоссияN.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian FederationRussian FederationФГБУ «НМИЦ кардиологии»РоссияA.L.Myasnikov Institute of Clinical Cardiology National Medical Research Center of Cardiology of the Ministry of Health of the Russian FederationRussian FederationФГАОУ ВО «Первый МГМУ им. И.М.Сеченова»РоссияI.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationRussian FederationФГАОУ ВО «Первый МГМУ им. И.М.Сеченова», ГБУЗ г. Москвы «ГКБ №1 им. Н.И.Пирогова»РоссияI.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationRussian FederationФГБУ «НМИЦ онкологии им. Н.Н.Блохина»РоссияN.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian FederationRussian FederationФГБУ «НМИЦ онкологии им. Н.Н.Блохина», ФГБОУ ДПО РМАНПОРоссияN.N.Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation; Russian Medical Academy of Continuous Professional Education of the Ministry of Health of the Russian FederationRussian Federation201723122022144619Copyright © Чазова И.Е., Тюляндин С.А., Виценя М.В., Полтавская М.Г., Гиляров М.Ю., Мартынюк Т.В., Овчинников А.Г., Панченко Е.П., Федоткина Ю.А., Стенина М.Б., Трофимова О.П., Агеев Ф.Т., 20222022Чазова И.Е., Тюляндин С.А., Виценя М.В., Полтавская М.Г., Гиляров М.Ю., Мартынюк Т.В., Овчинников А.Г., Панченко Е.П., Федоткина Ю.А., Стенина М.Б., Трофимова О.П., Агеев Ф.Т.Chazova I.Y., Tyulyandin S.A., Vitsenia M.V., Poltavskaya M.G., Gilyarov M.Y., Martynyuk T.V., Ovchinnikov A.G., Panchenko E.P., Fedotkina Y.A., Stenina M.B., Trophimova O.P., Ageev F.T.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.syst-hypertension.ru/jour/article/view/523

Достижения в лечении онкологических заболеваний привели к повышению выживаемости больных со злокачественными новообразованиями. В то же время противоопухолевая терапия сопряжена с риском развития побочных эффектов, среди которых сердечно-сосудистые осложнения занимают лидирующие позиции. Дисфункция левого желудочка и сердечная недостаточность, артериальная гипертония, ишемия миокарда, нарушения ритма сердца, тромбоэмболии и другие сердечно-сосудистые осложнения могут препятствовать проведению жизненно важной противоопухолевой терапии, снижать выживаемость и качество жизни больных. В представленном руководстве отражены диагностические и терапевтические подходы к ведению больных онкологического профиля, получающих потенциально кардиотоксичную противоопухолевую терапию. Вторая часть руководства посвящена вопросам диагностики, профилактики и лечения ишемической болезни сердца, артериальной гипертонии, нарушений ритма и проводимости сердца и легочной артериальной гипертензии, связанных с противоопухолевой терапией.

Advances in treatment have led to improved survival of patients with cancer but have also resulted in untoward side effects associated with treatment. Cardiovascular diseases are one of the most frequent of these side effects. Myocardial dysfunction and heart failure, myocardial ischaemia, arrhythmias, arterial hypertension, thromboembolic disease and other cardiovascular complications can interfere with the efficacy of treatment, decrease quality of life, or impact the actual survival of the patient with cancer. This manual discusses concepts for timely diagnosis, intervention, and surveillance of patients treated with cardiotoxic cancer therapies. In this second part оf manual we discuss the diagnostic, prevention and treatment aspects of cancer therapy-related coronary artery disease, arterial hypertension, arrhythmias and pulmonary hypertension.

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The authors declare that there are no conflicts of interest present.