systhiperСистемные гипертензииSystemic Hypertension2075-082X2542-2189LLC «ИнтерМедсервис»10.26442/2075-082X_2018.2.55-59systhiper-546Research ArticleСТАТЬИARTICLESПрофилактика инсульта у пациента с фибрилляцией предсердий и сопутствующими заболеваниямиStroke prevention in patients with atrial fibrillation and comorbiditiesОстроумоваО. Д.OstroumovaO. D.ostroumova.olga@mail.ruВоеводинаН. Ю.VoevodinaN. Yu.gkb-mukhina@zdrav.mos.ruГусеваТ. Ф.GusevaT. F.tguseva65@mail.ruПавлееваЕ. Е.PavleevaE. E.pavleeva.elena@mail.ruПиксинаГ. Ф.PiksinaG. F.galina-piksina@yandex.ruГолобородоваИ. В.GoloborodovaI. V.giv55555@ramler.ruФГБОУ ВО «МГМСУ им. А.И.Евдокимова», ФГАОУ ВО «Первый МГМУ им. И.М.Сеченова»РоссияA.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian Federation; I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationRussian FederationГБУЗ «ГКБ им. Е.О.Мухина»РоссияE.O.Muhin City Clinical Hospital of the Department of Health of MoscowRussian FederationФГБОУ ВО «МГМСУ им. А.И.Евдокимова»РоссияA.I.Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of the Russian FederationRussian Federation2018231220221525559Copyright © Остроумова О.Д., Воеводина Н.Ю., Гусева Т.Ф., Павлеева Е.Е., Пиксина Г.Ф., Голобородова И.В., 20222022Остроумова О.Д., Воеводина Н.Ю., Гусева Т.Ф., Павлеева Е.Е., Пиксина Г.Ф., Голобородова И.В.Ostroumova O.D., Voevodina N.Y., Guseva T.F., Pavleeva E.E., Piksina G.F., Goloborodova I.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.syst-hypertension.ru/jour/article/view/546

В статье рассмотрены вопросы профилактики инсульта, в том числе повторного. Обсуждается выбор антикоагулянтной терапии у больных с фибрилляцией предсердий и рядом сопутствующих заболеваний - ишемической болезнью сердца, сахарным диабетом, хронической болезнью почек, хронической сердечной недостаточностью. Приведены данные субанализов рандомизированного клинического исследования ARISTOTLE, свидетельствующие о высоком профиле эффективности и безопасности нового орального антикоагулянта апиксабана у данных категорий больных.

In the article questions of prevention of stroke, including repeated ones, are considered. The choice of anticoagulant therapy is discussed in patients with atrial fibrillation and a number of concomitant diseases - coronary artery disease, diabetes mellitus, chronic kidney disease, chronic heart failure. The data of subanalyses of a randomized clinical trial of ARISTOTLE are presented, indicating a high profile of efficacy and safety of the new oral anticoagulant apixaban in these categories of patients.

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The authors declare that there are no conflicts of interest present.