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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26442/2075-082X_2018.3.11-13</article-id><article-id custom-type="elpub" pub-id-type="custom">systhiper-552</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARTICLES</subject></subj-group></article-categories><title-group><article-title>Резистентная и рефрактерная артериальные гипертонии: сходства и различия, новые подходы к диагностике и лечению</article-title><trans-title-group xml:lang="en"><trans-title>Resistant and refractory arterial hypertension: similarities and differences, new approaches to diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аксенова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Aksenova</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">ksenovaannav@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Есаулова</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Esaulova</surname><given-names>T. E.</given-names></name></name-alternatives><email xlink:type="simple">yestatyana@gmai.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сивакова</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sivakova</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">ya.olga-siv2012@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чазова</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Chazova</surname><given-names>I. E.</given-names></name></name-alternatives><email xlink:type="simple">c34h@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «НМИЦ кардиологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center of Cardiologyof the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>15</volume><issue>3</issue><fpage>11</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аксенова А.В., Есаулова Т.Е., Сивакова О.А., Чазова И.Е., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Аксенова А.В., Есаулова Т.Е., Сивакова О.А., Чазова И.Е.</copyright-holder><copyright-holder xml:lang="en">Aksenova A.V., Esaulova T.E., Sivakova O.A., Chazova I.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/552">https://www.syst-hypertension.ru/jour/article/view/552</self-uri><abstract><p>Рефрактерная артериальная гипертония (АГ) - особый фенотип АГ, устойчивый к проводимой антигипертензивной терапии. Термины «рефрактерная АГ» и «резистентная АГ» зачастую считают взаимозаменяемыми и используют в отношении АГ, трудно поддающейся лечению. Группа пациентов с рефрактерной АГ, т.е. больных, не достигающих целевых цифр артериального давления на фоне максимальной антигипертензивной терапии, очень мала. Настоящий обзор посвящен сравнению сходных и контрастных черт в определениях, частоте встречаемости, характеристике пациентов, факторах риска и возможных этиологиях.</p></abstract><trans-abstract xml:lang="en"><p>Refractory hypertension is a novel phenotype of antihypertensive treatment failure. The terms "refractory hypertension" and "resistant hypertension" were considered interchangeable for a long time and related to difficult-to-treat hypertension. Recently, the term "refractory hypertension" refers to a very small group of patients who do not really reach the target blood pressure for maximum antihypertensive therapy. In this review we discuss similarities and contrasts definition, prevalence, patient characteristics, risk factors, and possible underlying etiologies of refractory and resistant hypertension.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рефрактерная артериальная гипертония</kwd><kwd>резистентная артериальная гипертония</kwd><kwd>антигипертензивная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>refractory hypertension</kwd><kwd>resistant hypertension</kwd><kwd>antihypertensive therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Calhoun D.A, Jones D, Textor S et al. Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. 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