systhiperСистемные гипертензииSystemic Hypertension2075-082X2542-2189LLC «ИнтерМедсервис»10.26442/2075082X.2019.3.190540systhiper-592Research ArticleСТАТЬИARTICLESХарактеристика гендерных особенностей клинической картины синдрома обструктивного апноэ сна и качества жизни больныхGender characteristics of obstructive sleep apnea syndrome clinical manifestations and patients' quality of lifeХачатрянН. Т.KhachatryanN. T.noemail@neicon.ruЕлфимоваЕ. М.ElfimovaE. M.eelfimova@gmail.comМихайловаО. О.MikhailovaO. O.noemail@neicon.ruЛитвинА. Ю.LitvinA. Yu.noemail@neicon.ruhttps://orcid.org/0000-0002-9822-4357ЧазоваИ. Е.ChazovaI. E.noemail@neicon.ruФГБУ «НМИЦ кардиологии»РоссияNational Medical Research Center of CardiologyRussian FederationФГБУ «НМИЦ кардиологии»; ФГБОУ ВО «РНИМУ им. Н.И. Пирогова»РоссияNational Medical Research Center of Cardiology; Pirogov Russian National Research Medical UniversityRussian Federation2019231220221635357Copyright © Хачатрян Н.Т., Елфимова Е.М., Михайлова О.О., Литвин А.Ю., Чазова И.Е., 20222022Хачатрян Н.Т., Елфимова Е.М., Михайлова О.О., Литвин А.Ю., Чазова И.Е.Khachatryan N.T., Elfimova E.M., Mikhailova O.O., Litvin A.Y., Chazova I.E.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.syst-hypertension.ru/jour/article/view/592

Синдром обструктивного апноэ сна (СОАС) - социально значимое заболевание, приводящее к увеличению риска развития сердечно-сосудистых осложнений и драматически ухудшающее качество жизни пациента. Длительное время заболевание считалось исключительно мужским, однако результаты эпидемиологических исследований последних лет отражают уменьшение разницы в заболеваемости между мужчинами и женщинами. Данные изменения обусловлены более прицельным изучением особенностей манифестации и клинического течения заболевания, а также новыми подходами к диагностике СОАС. Обзор посвящен анализу последних данных о гендерных различиях в распространенности, патофизиологии СОАС, диагностике и клинике заболевания. Также рассматриваются особенности влияния гендера на качество жизни и сна. Полученные результаты позволят лучше объяснить механизмы гендерных различий, а также сформировать новые тенденции в разработке клинических исследований.

Obstructive sleep apnea - is a socially significant disease that leads to an increased risk of developing cardiovascular complications and dramatically worsens the patient's quality of life. For a long time, the disease was considered exclusively male, however, the results of recent epidemiological studies reflect a decrease in the difference of the incidence between men and women. These changes are due to a more targeted study of the manifestations and clinical course of the disease, as well as new approaches in the diagnosis of obstructive sleep apnea syndrome. The review is focused on the analysis of recent data on gender differences in the prevalence, pathophysiology of obstructive sleep apnea, diagnostic approaches and clinical manifestation of the disease. It also considers the impact of gender on the quality of life and sleep. The obtained results can help better explain the mechanisms of gender differences, as well as form new trends in the development of clinical trials.

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The authors declare that there are no conflicts of interest present.