References

systhiper

Системные гипертензии

Systemic Hypertension

2075-082X2542-2189

LLC «ИнтерМедсервис»

10.26442/2075082X.2019.4.190686

systhiper-593

Research Article

КАРДИОЛОГИЯ

CARDIOLOGY

Консенсус по ведению пациентов с гиперурикемией и высоким сердечно-сосудистым риском

Consensus on patients with hyperuricemia and high cardiovascular risk treatment

https://orcid.org/0000-0002-9822-4357

Чазова

И. Е.

Chazova

I. E.

c34h@yandex.ru

https://orcid.org/0000-0001-7895-9068

Жернакова

Ю. В.

Zhernakova

J. V.

noemail@neicon.ru

Кисляк

О. А.

Kisliak

O. A.

noemail@neicon.ru

Недогода

С. В.

Nedogoda

S. V.

nedogodasv@rambler.ru

https://orcid.org/0000-0002-0758-5609

Подзолков

В. И.

Podzolkov

V. I.

noemail@neicon.ru

Ощепкова

Е. В.

Oshchepkova

E. V.

arthyplab@list.ru

Медведева

И. В.

Medvedeva

I. V.

noemail@neicon.ru

Миронова

О. Ю.

Mironova

O. Iu.

olgav39@yandex.ru

https://orcid.org/0000-0001-5215-4894

Блинова

Н. В.

Blinova

N. V.

nat-cardio1@yandex.ru

ФГБУ «НМИЦ кардиологии»РоссияNational Medical Research Center of CardiologyRussian Federation

ФГАОУ ВО «РНИМУ им. Н.И. Пирогова»РоссияPirogov Russian National Research Medical UniversityRussian Federation

ФГБОУ ВО ВолгГМУРоссияVolgograd State Medical UniversityRussian Federation

ФГАОУ ВО «Первый МГМУ им. И.М. Сеченова» (Сеченовский Университет)РоссияSechenov First Moscow State Medical University (Sechenov University)Russian Federation

ГБОУ ВО ТГМУРоссияTyumen State Medical UniversityRussian Federation

2019

23122022

164821

2022

Чазова И.Е., Жернакова Ю.В., Кисляк О.А., Недогода С.В., Подзолков В.И., Ощепкова Е.В., Медведева И.В., Миронова О.Ю., Блинова Н.В.

Chazova I.E., Zhernakova J.V., Kisliak O.A., Nedogoda S.V., Podzolkov V.I., Oshchepkova E.V., Medvedeva I.V., Mironova O.I., Blinova N.V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.syst-hypertension.ru/jour/article/view/593

Значительное количество эпидемиологических исследований продемонстрировало, что гиперурикемия в высокой степени связана с риском развития сердечно-сосудистых заболеваний, хронической болезни почек и сахарного диабета, в связи с чем необходимо повышенное внимание к мониторингу уровня мочевой кислоты в сыворотке крови у пациентов не только с точки зрения ревматических болезней, но также и в отношении снижения сердечно-сосудистого и почечного риска. Эксперты Европейского общества кардиологов и Российского медицинского общества по артериальной гипертонии включили в рутинные тесты измерение концентрации мочевой кислоты в сыворотке крови у больных артериальной гипертонией. Важным шагом на пути улучшения контроля гиперурикемии в клинической практике являются повышение осведомленности о гиперурикемии как о факторе риска сердечно-сосудистых заболеваний, разработка алгоритма ведения больных с гиперурикемией и высоким сердечно-сосудистым риском, повышение приверженности рекомендациям. Снижение уровня мочевой кислоты в сыворотке крови, достигнутое посредством лечения пациентов уратснижающими препаратами, главным образом ингибитором ксантиноксидазы, связано с улучшением контроля артериального давления и уменьшением частоты нежелательных сердечно-сосудистых событий.

Substantial amount of epidemiologic studies showed that hyperuricemia is highly associated with cardiovascular disorders, chronic renal disease, and diabetes mellitus development risk. This fact shows necessity of increased focus on uric acid level in serum not only in relation to rheumatic disorders but also in relation to cardiovascular and renal risk. European Society of Cardiology and Russian Arterial Hypertension Society experts included tests on uric acid level serum concentration in routine tests for hypertensive patients. Important steps in increase of hyperuricemia control in clinical practice are increase of awareness as a risk factor of cardiovascular disorders, development of risk management algorithm for patients with hyperuricemia and high cardiovascular risk, and increase of treatment adherence. Decrease of uric acid level in serum achieved after treatment with urate decreasing therapy mostly with xanthine oxidase inhibitor is associated with improvement of blood pressure control and decrease of cardiovascular adverse events frequency.

гиперурикемиямочевая кислотафактор рискасердечно-сосудистый рискартериальная гипертонияингибитор ксантиноксидазыаллопуринол

hyperuricemiauric acidrisk factorcardiovascular riskarterial hypertensionxanthine oxidase inhibitorallopurinol

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The authors declare that there are no conflicts of interest present.