<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">systhiper-61</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Выбираем beta-адреноблокатор для пациента с артериальной гипертонией</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чазова</surname><given-names>И. Е.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ратова</surname><given-names>Л. Г.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартынюк</surname><given-names>Т. В.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Институт кардиологии им. Мясникова РКНПК МЗ и СР РФ</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2005</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2022</year></pub-date><volume>3</volume><issue>2</issue><fpage>48</fpage><lpage>52</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чазова И.Е., Ратова Л.Г., Мартынюк Т.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Чазова И.Е., Ратова Л.Г., Мартынюк Т.В.</copyright-holder><copyright-holder xml:lang="en">Чазова И.Е., Ратова Л.Г., Мартынюк Т.В.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/61">https://www.syst-hypertension.ru/jour/article/view/61</self-uri><abstract><p>От имени исследовательской группы - Основная идея исследования КОРИФЕЙ – это оптимизация лечения больных АГ с применением современных высокоэффективных антигипертензивных препаратов длительного действия, как в виде моно -, так и комбинированной терапии. Не менее важным представляется вопрос о сопоставимости результатов самоконтроля АД, клинического (офисного) АД и СМАД на фоне лечения, так как основным методом оценки эффективности антигипертензивной терапии у больных в обычной поликлинике является клиническое АД, реже клиническое АД плюс самоконтроль и еще реже СМАД. Цели исследования:    • Изучить антигипертензивную эффективность и безопасность терапии карведилолом (кориол, КРКА) у больных АГ в разных возрастных группах при наличии или отсутствии ХОБЛ.    • Сравнить эффективность и безопасность применения карведилола, как монотерапии, так и в комбинации с амлодипином (тенокс, КРКА) с произвольной антигипертензивной терапией.    • Изучить сопоставимость результатов самоконтроля АД, клинического (офисного) АД и суточного мониторирования АД (СМАД).</p></abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сидоренко Б.А., Преображенский Д.В. Бета - адреноблокаторы. Практическая кардиология. М., 1996.</mixed-citation><mixed-citation xml:lang="en">Сидоренко Б.А., Преображенский Д.В. Бета - адреноблокаторы. Практическая кардиология. М., 1996.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">WHCMSH Third Mild Hypertension Confirence of the treatment of mild hypertension: Memorandum from a WHO/ISH meeting. Bull World Health Organ 1983; 61: 53–6.</mixed-citation><mixed-citation xml:lang="en">WHCMSH Third Mild Hypertension Confirence of the treatment of mild hypertension: Memorandum from a WHO/ISH meeting. Bull World Health Organ 1983; 61: 53–6.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Subcommittee on Definition and Prevalence of the 1984 Joint National Committee. Hypertension prevalence and the status awareness, teatment, and cjntrol in the United States: Final report of the Subcommitee on Definition and Prevalence of the 1984 Joint National Committee. Hypertension 1985; 7: 457–68.</mixed-citation><mixed-citation xml:lang="en">Subcommittee on Definition and Prevalence of the 1984 Joint National Committee. Hypertension prevalence and the status awareness, teatment, and cjntrol in the United States: Final report of the Subcommitee on Definition and Prevalence of the 1984 Joint National Committee. Hypertension 1985; 7: 457–68.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Singh B.N. Morbidity and mortality in cardiovascular disorders: impact of reduced heart rate.J Cardiovascular Pharmacol Therapeutics 2001; 6 (4): 313–31.</mixed-citation><mixed-citation xml:lang="en">Singh B.N. Morbidity and mortality in cardiovascular disorders: impact of reduced heart rate.J Cardiovascular Pharmacol Therapeutics 2001; 6 (4): 313–31.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Gillman M, Kannel W, Belanger A, D’Agostino R. Influence of heart rate on mortality among persons with hypertension: the Framingham Study. Am Heart J1993; 125: 1148–54.</mixed-citation><mixed-citation xml:lang="en">Gillman M, Kannel W, Belanger A, D’Agostino R. Influence of heart rate on mortality among persons with hypertension: the Framingham Study. Am Heart J1993; 125: 1148–54.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Julius S. Effect of sympathetic overactivity on cardiovascular prognosis in hypertension. Eur Heart J 1998; 19 (suppl. F): F14–F18.</mixed-citation><mixed-citation xml:lang="en">Julius S. Effect of sympathetic overactivity on cardiovascular prognosis in hypertension. Eur Heart J 1998; 19 (suppl. F): F14–F18.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kaplan N.M. Multiple risk factors for coronary heart disease in patients with hypertension. J Hypertension 1995; 13 (suppl. 2): S1–S5.</mixed-citation><mixed-citation xml:lang="en">Kaplan N.M. Multiple risk factors for coronary heart disease in patients with hypertension. J Hypertension 1995; 13 (suppl. 2): S1–S5.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Mc Innes G.T. Hypertension and coronary artery disease: cause and effect. J Hypertens 1995; 13 (suppl. 2): S49–S56.</mixed-citation><mixed-citation xml:lang="en">Mc Innes G.T. Hypertension and coronary artery disease: cause and effect. J Hypertens 1995; 13 (suppl. 2): S49–S56.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Doughty R.N, Mac Mahon S, Sharpe N. Beta - blockers in failure: promising or proved? Am Con Cardiol 1994; 23: 814–20.</mixed-citation><mixed-citation xml:lang="en">Doughty R.N, Mac Mahon S, Sharpe N. Beta - blockers in failure: promising or proved? Am Con Cardiol 1994; 23: 814–20.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">SHEP Cooperative Research Group.Prevention of stroke by antihypertensive drug treatment in older persons with isolated sistolic hypertension. Final results of the Systolic Hypertision in the Elderly Program (SHEP). JAMA 1991; 265: 3255–64.</mixed-citation><mixed-citation xml:lang="en">SHEP Cooperative Research Group.Prevention of stroke by antihypertensive drug treatment in older persons with isolated sistolic hypertension. Final results of the Systolic Hypertision in the Elderly Program (SHEP). JAMA 1991; 265: 3255–64.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Dahlof B, Lindholm L.H, Hansson L et al. Morbidity and mortality in the Swedish. Trial in Old Patients with Hypertension (STOP-Hypertension). Lancet 1991; 338: 1281–5.</mixed-citation><mixed-citation xml:lang="en">Dahlof B, Lindholm L.H, Hansson L et al. Morbidity and mortality in the Swedish. Trial in Old Patients with Hypertension (STOP-Hypertension). Lancet 1991; 338: 1281–5.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Рекомендации по профилактике, диагностике и лечению артериальной гипертензии. Российские рекомендации (второй пересмотр). Комитет экспертов Всероссийского научного общества кардиологов. Секция артериальной гипертонии ВНОК. М., 2004. Приложение к журналу "Кардиоваскулярная терапия и профилактика".</mixed-citation><mixed-citation xml:lang="en">Рекомендации по профилактике, диагностике и лечению артериальной гипертензии. Российские рекомендации (второй пересмотр). Комитет экспертов Всероссийского научного общества кардиологов. Секция артериальной гипертонии ВНОК. М., 2004. Приложение к журналу "Кардиоваскулярная терапия и профилактика".</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
