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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">systhiper</journal-id><journal-title-group><journal-title xml:lang="ru">Системные гипертензии</journal-title><trans-title-group xml:lang="en"><trans-title>Systemic Hypertension</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2075-082X</issn><issn pub-type="epub">2542-2189</issn><publisher><publisher-name>LLC «ИнтерМедсервис»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38109/2075-082X-2023-3-39-46</article-id><article-id custom-type="elpub" pub-id-type="custom">systhiper-792</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group></article-categories><title-group><article-title>Параметры жесткости сосудистой стенки у больных АГ с ожирением и нормальной массой тела после перенесенной новой коронавирусной инфекции</article-title><trans-title-group xml:lang="en"><trans-title>Arterial stiffness parameters in obesity and normal weight hypertensive patients after COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4269-4608</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кокаева</surname><given-names>И. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Kokaeva</surname><given-names>Izolda O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кокаева Изольда Омаровна, врач-кардиолог, аспирант отд. гипертонии,</p><p>ул. Академика Чазова, 15 А, Москва 121552. </p></bio><bio xml:lang="en"><p>Izolda O. Kokaeva, cardiologist, Graduate Student,</p><p>15A Akademika Chazova St., Moscow 121552. </p></bio><email xlink:type="simple">izolda.kokaeva@icloud.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7895-9068</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жернакова</surname><given-names>Ю. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhernakova</surname><given-names>Yuliya V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жернакова Юлия Валерьевна, д.м.н., ученый секретарь, </p><p>ул. Академика Чазова, 15 А, Москва 121552.</p></bio><bio xml:lang="en"><p>Yuliya V. Zhernakova, Prof., Dr. of Sci. (Med.), Scientific Secretary</p><p>15A Akademika Chazova St., Moscow 121552. </p></bio><email xlink:type="simple">juli001@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5917-0205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреевская</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreevskaya</surname><given-names>Marina V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андреевская Марина Владимировна, к.м.н., науч. сотр. отд. ультразвуковых методов исследования,</p><p>ул. Академика Чазова, 15 А, Москва 121552.</p></bio><bio xml:lang="en"><p>Marina V. Andreevskaya, Cand. of Sci. (Med.), Scientific Advisor, Cardiology,</p><p>15A Akademika Chazova St., Moscow 121552. </p></bio><email xlink:type="simple">marineracrim@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5215-4894</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блинова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Blinova</surname><given-names>Nataliya V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Блинова Наталия Владимировна, к.м.н., ст. науч. сотр. отд. гипертонии,</p><p>ул. Академика Чазова, 15 А, Москва 121552.</p></bio><bio xml:lang="en"><p>Nataliya V. Blinova, Cand. of Sci. (Med.), Senior Researcher, Department of Hypertension,</p><p>15A Akademika Chazova St., Moscow 121552. </p></bio><email xlink:type="simple">nat-cardio1@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Институт клинической кардиологии им. А.Л. Мясникова, ФГБУ «Национальный медицинский исследовательский центр кардиологии  им. академика Е.И. Чазова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>A.L. Myasnikov Institute of Clinical Cardiology, E.I. Chazov National Medical Research Center of Cardiology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>26</day><month>10</month><year>2023</year></pub-date><volume>20</volume><issue>3</issue><fpage>39</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кокаева И.О., Жернакова Ю.В., Андреевская М.В., Блинова Н.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Кокаева И.О., Жернакова Ю.В., Андреевская М.В., Блинова Н.В.</copyright-holder><copyright-holder xml:lang="en">Kokaeva I.O., Zhernakova Y.V., Andreevskaya M.V., Blinova N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.syst-hypertension.ru/jour/article/view/792">https://www.syst-hypertension.ru/jour/article/view/792</self-uri><abstract><sec><title>Цель</title><p>Цель: изучить и сопоставить функциональное состояние сосудистой стенки (скорость пульсовой волны, сердечно-лодыжечный сосудистый индекс) у больных артериальной гипертонией с ожирением и у больных артериальной гипертонией с нормальной массой тела через 1 месяц после перенесенной новой коронавирусной инфекции в среднетяжелой и тяжелой форме.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование включены 87 пациентов обоего пола, в возрасте от 18 до 55 лет, из которых сформированы три группы: в первую группу отобраны лица с АГ и нормальной массы тела (ИМТ&lt;25 кг/м²), перенесшие COVID-19 в течении месяца, вторая группа включала лиц с АГ и ожирением (ИМТ≥30 кг/м²), перенесших COVID-19 в течении месяца, контрольную группу составило 20 человек с АГ и ожирением без перенесенного COVID-19. Всем исследуемым проведена оценка параметров роста, веса, окружности талии, ИМТ. Определены параметры липидного профиля, уровня глюкозы. Всем пациентам проводилось офисное измерение систолического и диастолического АД. Артериальная жесткость определялась по данным CAVI (Cardio-Ankle Vascular Index), плече-лодыжечной скорости пульсовой волны – СПВпл (VaSera 1000), аортальной скорости пульсовой волны – СПВао (ультразвуковая система EnVisor).</p></sec><sec><title>Результаты</title><p>Результаты. СПВао значимо различалась между 1 и 2 группами (р&lt;0,001), в группе пациентов с АГ и ожирением СПВ составила 6,26 (5,17-7,26) м/сек, в группе без ожирения – 4,50 (4,21-5,10) м/сек. Установлены статистически значимые различия параметров ЛПИпр (p=0,020) по уровню CAVI: R-CAVI (р=0,012) и R-tb (p=0,026), L-CAVI (р=0,010) и L-tb (р=0,007). Между исследуемыми группами 1 и 2 выявлены статистически значимые различия по ЧСС (p=0,005).</p></sec><sec><title>Заключение</title><p>Заключение. По данным нашей работы, во видимому, вклад ожирения в состояние сосудистой стенки более значим, чем вклад COVID-19. Однако ухудшение показателей жесткости артерий приводит к худшим исходам COVID-19, что требует более тщательного подхода к диагностике состояния сосудистой стенки на ранних госпитальных этапах. Неинвазивная оценка жесткости артерий может помочь выявить лиц с риском клинического ухудшения.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To study and compare the functional state of the vascular wall (pulse wave velocity, cardiac-ankle vascular index) in obesity arterial hypertension patients and in arterial hypertension patients with normal body weight 1 month after a new coronavirus infection in moderate to severe form.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study included 87 patients of both sexes, aged from 18 to 55 years, from which three groups were formed: the first group included people with AH and normal body weight (BMI&lt;25 kg/m²) who had undergone COVID-19 within a month, the second group included people with AH and obesity (BMI≥30 kg/m²) who had undergone COVID-19 within a month, the control group consisted of 20 people with AH and obesity without COVID-19. The parameters of height, weight, waist circumference, and BMI were assessed in all subjects. The parameters of lipid profile, glucose level were determined. All patients underwent office measurement of systolic and diastolic BP. Arterial stiffness was determined according to CAVI (Cardio-Ankle Vascular Index), brachialankle pulse wave velocity – PWVba (VaSera 1000), aortic pulse wave velocity – PWVao (EnVisor ultrasound system).</p></sec><sec><title>Results</title><p>Results. PWVao significantly differed between groups 1 and 2 (p&lt;0,001), in the group of patients with AH and obesity PWV was 6,26 (5,17-7,26) m/sec, in the group without obesity – 4,50 (4,21-5,10) m/sec. Statistically significant differences were found in the parameters of ABIr (p=0,020), in the level of CAVI: R-CAVI (p=0,012) and R-tb (p=0,026), L-CAVI (p=0,010) and L-tb (p=0,007). Statistically significant differences in RHR were found between study groups 1 and 2 (p=0,005).</p></sec><sec><title>Conclusion</title><p>Conclusion. The contribution of obesity to vascular wall health appears to be more significant than that of COVID-19. However, worsening arterial stiffness scores lead to worse COVID-19 outcomes, which calls for a more thorough approach to diagnosing vascular wall health early in the hospital setting. Non-invasive assessment of arterial stiffness may help to determine those at risk of clinical deterioration.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>Артериальная гипертония</kwd><kwd>жесткость сосудов</kwd><kwd>скорость пульсовой волны</kwd><kwd>ожирение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>Arterial hypertension</kwd><kwd>arterial stiffness</kwd><kwd>pulse wave velocity</kwd><kwd>obesity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wu Z, McGoogan JM. 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