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Системные гипертензии

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Кандесартан в лечении артериальной гипертонии

Аннотация

Кандесартан является селективным блокатором рецепторов ангиотензина II 1-го типа. Отличительными особенностями его фармакокинетики и фармакодинамики являются большая продолжительность антигипертензивного действия, высокая селективность и хорошая биодоступность препарата. В лечении артериальной гипертонии кандесартан способен эффективно предотвращать утренний подъем артериального давления. Для препарата свойственны церебро-и кардиопротективные эффекты, способность снижать риск появления новых случаев сахарного диабета. Препарат оказывается эффективным средством в лечении нефропатии разного генеза, в том числе и у больных с выраженным снижением функции почек. Метаболическая нейтральность, способность предотвращать развитие микро-и макроангиопатии позволяют рекомендовать этот блокатор рецепторов ангиотензина в лечении больных сахарным диабетом. Благоприятный профиль фармакокинетических свойств создает преимущество кандесартана в эффективности по сравнению с другими препаратами той же группы.

Об авторе

Л. О. Минушкина
ФГБУ Учебно-научный медицинский центр Управления делами Президента РФ, Москва
Россия


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Рецензия

Для цитирования:


Минушкина Л.О. Кандесартан в лечении артериальной гипертонии. Системные гипертензии. 2014;11(1):25-29.

For citation:


Minushkina L.O. Candesartan in treating hypertension. Systemic Hypertension. 2014;11(1):25-29.

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