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Системные гипертензии

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Центральные и гуморальные механизмы формирования артериальной гипертензии у женщин

Аннотация

В статье обсуждаются разные механизмы развития артериальной гипертензии (АГ) у женщин в постменопаузе. Проанализированы литературные данные о влиянии половых гормонов, в том числе дефицита эстрогенов и прогестерона, избытка андрогенов на уровень артериального давления и метаболические параметры. Особое внимание уделено участию ренин-ангиотензин-альдостероновой системы в патогенезе АГ у женщин в перименопаузельном периоде. Отдельные разделы посвящены роли дисфункции вегетативной нервной системы и нарушений обмена биогенных аминов в формировании вегетативно-сосудистого симптомокомплекса в рамках климактерического синдрома, а также вкладу таких гуморальных сдвигов, характерных для центрального ожирения, как гиперинсулинемия и гиперлептинемия.

Об авторах

В. И. Подзолков
ГБОУ ВПО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава России
Россия


А. Е. Брагина
ГБОУ ВПО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава России
Россия


Ю. Н. Родионова
ГБОУ ВПО Первый Московский государственный медицинский университет им. И.М.Сеченова Минздрава России
Россия


Ю. А. Колода
ГБОУ ДПО Российская медицинская академия последипломного образования Минздрава России
Россия


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Рецензия

Для цитирования:


Подзолков В.И., Брагина А.Е., Родионова Ю.Н., Колода Ю.А. Центральные и гуморальные механизмы формирования артериальной гипертензии у женщин. Системные гипертензии. 2015;12(1):76-82.

For citation:


Podzolkov V.I., Bragina A.E., Rodionova J.N., Koloda J.A. Central and humoral mechanisms for arterial hypertension in women. Systemic Hypertension. 2015;12(1):76-82. (In Russ.)

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