Fibromuscular dysplasia as the cause of malignant renovascular hypertension in a newborn

Abstract

Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory arteriopathy, which can affect arteries of any part of vascular system and is most commonly diagnosed in women between 20-60 years of age. We present the FMD case study of ischemic stroke in a 10-month-old child, manifested in the hospital. The application of diagnostic methods is not allowed to determine the cause of uncontrolled arterial hypertension development in patient during the life. Pathologic study revealed the generalized tubular fibromuscular vascular dysplasia affecting arterial vessels practically of all parts of vascular system and forming stenotic areas of both of the renal arteries, the arteries of the heart, brain, intestines, liver and spleen.Conclusion. FMD manifestation during the period of infancy is associated with severe course and poor prognosis. The improvement of the prognosis for this disease, obviously, can be achieved in case of the diagnosis the disease before the development of organ complications, what is required the monitoring of blood pressure level during the routine pediatric examinations in children of the first year of life, even in the absence of complaints.