Abdominal visceral adipose tissue ultrasound assessmet as a tool in predicting of high cardiometric risk obesity

Objective: to conduct the analysis of association abdominal visceral adipose tissue ultrasound indices with parameters of cardiovascular remodeling and metabolic risk factors with subsequent evaluation of their use as a predictor of high cardiometabolic risk obesity. Material and methods. Totally, 274 normotensive males investigated (mean age 44.8±5.0 y. o.), with no clinical signs of cardiovascular disorders and type 2 diabetes, with the SCORE risk <5% and abdominal obesity. The assessment included the analysis of metabolic risk factors, ultrasound assessment of abdominal adipose tissue thickness and its ratio to subcutaneous fat thickness, echocardiography, brachiocephalic arteries triplex scanning, bifunctional 24-hour blood pressure monitoring. Results. The association revealed, of the abdominal visceral adipose tissue ultrasound indices with metabolic risk factors and parameters of cardiovascular remodeling, more strong compared with the waist circumference. Patients with the ratio of the ultrasonic abdominal visceral adipose tissue thickness to subcutaneous fat thickness ≥3.0 (n=77) were different (comparing to the group in general) by higher rate of hypertrophy existence (31.2% vs 11.7%, p<0.001) and diastolic dysfunction of the left ventricle (40.3% vs 16.8%, p<0.001), hypertrophy of the intima-media of carotid artery (49.4% vs 29.2%, p<0.001), carotid atherosclerosis (46.8% vs 18.2%, p<0.001), prediabetes (39.0% vs 16.1%, p<0.01), high grades albuminuria (24.7% vs 9.1%, р<0.001). An equation predictive estimates of the ratio of the ultrasonic abdominal visceral adipose tissue thickness to subcutaneous fat thickness: waist circumference × 0.006 + fusting blood glucose × 0.192 + total cholesterol × 0.115 + uric acid × 1.187. Conclusions. In asymptomatic for CVD patients the presence of visceral obesity, verified on the ultrasound indices of abdominal visceral adipose tissue assessment, indicates a high probability of metabolic disorders and subclinical organ disorders. The ratio of the ultrasonic abdominal visceral adipose tissue thickness to subcutaneous fat thickness can act as an index of visceral obesity, whose value ≥3.0 allows us to speak about the most likely high cardiometabolic risk

visceral adipose tissue, visceral obesity, cardiometabolic risk

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