Possibilities of a new glucagon-like peptide-1 receptor agonist Semaglutide in improving left ventricular diastolic function in a patient with arterial hypertension and type 2 diabetes mellitu
https://doi.org/10.26442/2075082X.2021.4.201305
Abstract
The emergence of new classes of glucose-lowering drugs that can further reduce cardiovascular risk (CVR) have fundamentally changed the approach to the management of patients with type 2 diabetes mellitus. The most significant changes concerned the strategy of choosing glucose-lowering therapy with a change in priorities from the glycemia level to CVR, which plays a key role in choosing a class of antidiabetic drugs. At the same time, the mechanisms responsible for lowering CVR remain largely unclear. Of undoubted interest is the study of effects of a new glucagon-like peptide-1 receptor agonist, Semaglutide, on the preclinical stage of diastolic dysfunction. The article presents a clinical case of the use of Semaglutide in a patient with arterial hypertension and type 2 diabetes mellitus.
About the Authors
M. R. Azimova
Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology
Russian Federation
Russian Federation
J. V. Zhernakova
Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology
Russian Federation
Russian Federation
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Review
For citations:
Azimova M.R., Zhernakova J.V. Possibilities of a new glucagon-like peptide-1 receptor agonist Semaglutide in improving left ventricular diastolic function in a patient with arterial hypertension and type 2 diabetes mellitu. Systemic Hypertension. 2021;18(4):186-192. (In Russ.) https://doi.org/10.26442/2075082X.2021.4.201305
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