Preview

Systemic Hypertension

Advanced search

The influence of anxiety and depressive disorders on the development of resistant arterial hypertension

https://doi.org/10.38109/2075-082X-2024-2-49-55

Abstract

   The problem of comorbidity of cardiovascular diseases (CVD) and anxiety-depressive disorders is actively discussed in modern scientific literature. Taking into account the widespread prevalence of anxiety and depressive disorders in the population, their negative impact on the quality of life and functioning of patients, prerequisites are accumulating for the diagnosis and treatment of these conditions by non-psychiatric doctors. The review presents current data on risk factors, relationships and principles for diagnosing resistant arterial hypertension (RAH) and anxiety-depressive disorders. The prevalence of resistant arterial hypertension is about 10–20 %, with a significant proportion of cases accounting for secondary arterial hypertension and pseudoresistance. The incidence of anxiety and depressive disorders in patients with arterial hypertension is 42 % and 52 %, respectively. The prevalence of anxiety and depressive disorders in RAH is 36.8 %. Such comorbidity contributes to the progression of PAH, worsens the patient’s prognosis, and reduces adherence to therapy. Given the close relationship between psychoemotional factors and CVD, patients with RAH are advised to undergo screening for anxiety and depression.

About the Authors

Ju. V. Pchelenok
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Julia V. Pchelenok, therapist, clinical resident

the Faculty of Medicine; Department of faculty therapy number 1

119435;  6 Bolshaya Pirogovskaya street, building 1; Moscow



A. V. Fomicheva
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Anastasia V. Fomicheva, psychiatrist, graduate student

the Faculty of Medicine; Department of psychiatry and psychosomatics

119021; 11 Rossolimo street, building 9; Moscow



M. Kanaeva
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Medine Kanaeva, student

the Faculty of Medicine; the Department of faculty therapy number 1

119435;  6 Bolshaya Pirogovskaya street, building 1; Moscow



A. V. Rodionov
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Anton V. Rodionov, Cand. of Sci. (Med.), docent

the Faculty of Medicine; Department of faculty therapy number 1

119435;  6 Bolshaya Pirogovskaya street, building 1; Moscow



A. O. Tolokonin
Clinic «Neo-vita»
Russian Federation

Artеm O. Tolokonin, Cand. of Sci. (Med.), the chief physician

121609;  45 Krylatskaya street, building 1; Moscow



B. A. Volel
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation

Beatrice A. Volel, Dr. of Sci. (Med.), Professor, Director, Senior Researcher

Institution of Scientific Research Mental Health Research Centre; Department of Psychiatry and Psychosomatics

119021; 11 Rossolimo street, building 9; Moscow



References

1. Guillaume L., Mathieu A., Mélanie D., Resistant Hypertension: Novel Insights». CurrHypertensRev. 2020;16(1):61-72. doi: 10.2174/1573402115666191011111402

2. Ettehad D., Connor A.Е., Simon G.A. et al. Blood pressure lowering for prevention of cardiovascular disease and death : a systematic review and meta-analysis. Lancet. 2016 Mar 5;387(10022):957-967. doi: 10.1016/S0140-6736(15)01225-8

3. Gupta, Ajay K.; Nasothimiou, Efthimia G.; Chang, Choon L.; Sever, Peter S.; Dahlöf, Bjorn; Poulter, Neil R. on behalf of the ASCOT investigators. Baseline predictors of resistant hypertension in the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT): a risk score to identify those at high-risk. Journal of Hypertension. October 2011;29(10):2004-2013. doi: 10.1097/HJH.0b013e32834a8a42

4. Podzolkov V. I., Bragina A. E., Medvedev I. D., Vetluzhskaya M. V., Abramova A. A., Loria I. Zh., Megeneishvili N. K., Sutulova A.V. Compliance to treatment and its role in solving the problem of uncontrolled hypertension. Cardiovascular Therapy and Prevention. 2023;22(4):3547. doi: 10.15829/1728-8800-2023-3547

5. Rodionov AV, Yudin IG, Fomin VV. Resistant arterial hypertension. Consilium Medicum. 2021;23(1):28–31. (in Russ.) URL: https://cyberleninka.ru/article/n/rezistentnaya-arterialnaya-gipertenziya-1?ysclid=lxvpy1eurq117912836

6. Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD, White A, Cushman WC, White W, Sica D, Ferdinand K, Giles TD, Falkner B, Carey RM. Resistant hypertension: diagnosis, evaluation, and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension. 2008 Jun;51(6):1403-19. Epub 2008 Apr 7. PMID: 18391085. doi: 10.1161/HYPERTENSIONAHA.108.189141

7. Burnier M, Egan BM. Adherence in Hypertension. CircRes. 2019;124(7):1124-1140. doi: 10.1161/CIRCRESAHA.118.313220

8. Volel BA, Troshina DV. Somatic depression with cognitive impairment in a female patient with hypertension. Nevrologiya, neiropsikhiatriya, psikhosomatika = Neurology, neuropsychiatry, psychosomatics. 2017;9(4):60–64. doi: 10.14412/2074-2711-2017-4-60-64

9. Iancu M.A., Mateiciuc I.I., Stanescu A.M., et al. Therapeutic Compliance of Patients with Arterial Hypertension in Primary Care. Medicina. 2020;56(11);631. doi: 10.3390/medicina56110631

10. Mancia G., Fagard R., Narkiewicz K, et al. ESH-ESC Task Force on the Management of Arterial Hypertension. 2013 ESH-ESC Practice Guidelines forthe Management of ArterialHypertension: ESH-ESC Task Force on the Management of Arterial Hypertension. Eur Heart J 2013;34(28):2159-219. doi: 10.1093/eurheartj/eht151

11. Yugar-Toledo J.C., Vilela J.В., Martin, J et al. Gene Variation in Resistant Hypertension: Multilocus Analysis of the Angiotensin 1-Converting Enzyme, Angiotensinogen, and Endothelial Nitric Oxide Synthase Genes. DNA Cell Biol. 2011;30(8):555-64. doi: 10.1089/dna.2010.1156

12. Tolokonin A.O., Petelin D.S., Anpilogova E.M., Volel B.A. Тhe assessment of psychotrauma’s role in the development of different kinds of diseases: a pilot online study. Journal of Social and Clinical Psychiatry. 2023;(33):31-38. (in Russ.) doi: 10.34757/0869-4893.2023.33.4.004

13. Depression in patients with arterial hypertension and its impact on quality of life : abstract of thesis. ... Candidate of Medical Sciences: 14.00.06, 14.00.13 / Moscow. state med.-dentist. univ. - Moscow, 2005. - 25 p.

14. Shtarik S.Yu., Petrova M.M., Garganeyeva N.P. Some aspects of comorbidity of anxious-depressive disorders and arterial hypertension. Siberian Medical Journal. 2009;24:46-48. (in Russ.)

15. Goodwin R.D., Davidson K.W., Keyes K. Mental disorders and cardiovascular disease among adults in the United States. J Psychiatr Res. 2009 Jan;43(3):239-46. doi: 10.1016/j.jpsychires.2008.05.006

16. Ferreira M.A., O’Donovan M., Meng Y.A., et al. Wellcome Trust Case Control Consortium. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 2008; 40:1056-1058. PMID: 18711365; PMCID: PMC2703780. doi: 10.1038/ng.209

17. Teplova N.V., Putilin M.V. Secondary Neurogenic Hypertension as a Cause of Cognitive Impairment. Opportunities for Therapeutic Correction. General Medicine. 12022;1:32-38. (in Russ.) doi: 10.24412/2071-5315-2022-12489

18. Spruill T.M., Butler M.J., Thomas S.J., et al. Association Between High Perceived Stress Over Time and Incident Hypertensionin Black Adults: Findings From the Jackson Heart Study. JAmHeartAssoc. 2019;8(21):e012139. doi: 10.1161/JAHA.119.012139

19. Bautista L.E., Bajwa P.K., Shafer M.M., et al.The relationship between chronic stress, hair cortisol and hypertension. International JCardiolHypert. 2019;2:100012. doi: 10.1016/j.ijchy.2019.100012

20. Kőrӧsi B., Gyӧngyӧsi H., Batta D., et al. Evaluation of affective temperaments and arterial stiffness in different hypertension phenotypes. Hypertension Research. 2021;44:47–54. doi: 10.1038/s41440-020-0513-2

21. Slopen N., Kubzansky L.D., McLaughlin K.A., et al. Childhood adversity and inflammatory processes in youth: A prospective study. Psychoneuroendocrinology. 2013;38:188–200. doi: 10.1016/j.psyneuen.2012.05.013

22. Levin O.S. Anxiety disorders in general clinical practice. Medical advice. 2017;(10):36-40. (in Russ.) doi: 10.21518/2079-701X-2017-10-36-40

23. Starostina E.G.. Anxiety and anxiety disorders in cardiology practice. Cardiovascular therapy and prevention. 2006;5(3):111-120. (in Russ.)

24. Kubzansky LD, Kawachi I. Going to the heart of the matter: do negative emotions cause coronary heart disease? J Psychosomatic Research. 2000;48(4-5):323-337. doi: 10.1016/S0022-3999(99)00091-4

25. Paterniti S, Alperovich A, Ducimetiere P, et al. Anxiety, but not depression is associated with elevated blood pressure in a community group of French elderly. Psychosom Med 1999; 61:77-83. doi: 10.1097/00006842-199901000-00013

26. Jonas B.S., Franks P, Ingram D.D. Are symptoms of anxiety and depression risk factors for hypertension? Longitudinal evidencefrom the National Health and Nutrition Examination Survey Iepidemiologic follow-up study. Arch Fam Med 1997;6:43-9. doi: 10.1001/archfami.6.1.43

27. Johnson H.M. Anxiety and hypertension: Is there a link? A literature review of the comorbidity relationship between anxiety and hypertension. CurrHypertens Rep. 2019;21(9):66. doi: 10.1007/s11906-019-0972-5

28. Pan Y., Cai W., Cheng Q., et al. Association between anxiety and hypertension : a systematic review and meta-analysis of epidemiological studies Neuropsychiatr Dis Treat. 2015 Apr 22:11:1121-30. doi: 10.2147/NDT.S77710

29. Mehmet E.Ö., Ebru Ö., Nazile B.D. et al. Impact of anxiety level on circadian rhythm of blood pressure in hypertensive patients 1. Int J ClinExp Med. 2015; 8(9): 16252–16258.

30. Tsartsalis D, Dragioti E, Kontoangelos K, et al. The impact of depression and cardiophobia on quality of life in patients with essential hypertension. Psychiatriki. 2016;192-203. doi: 10.22365/jpsych.2016.273.192

31. Schmieder R.E., Grassi G., Kjeldsen S.E. Patients with treatment-resistant hypertension report increased stress and anxiety: a worldwide study. J Hypertens 2013;31(3):610-5; discussion 615. doi: 10.1097/HJH.0b013e32835d6e53

32. Smulevich AB, Volel' BA, Ternovaia ES, Nikitina YuM. Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension. S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(12):40-49. (In Russ.) doi: 10.17116/jnevro201511511240-49

33. Borovkov N., Berdnikova L., Dobrotina I. Treatment for anxiety and depressive disorders in patients with cardiovascular diseases. Vrach. 2013;(12):53-58. (in Russ.) EDN: RQEDRR

34. Jhalani J., Goyal T., Clemow L., et al. Anxiety and outcome expectations predict the white-coat effect. Blood Press Monit. 2005 Dec;10(6):317-9. PMID: 16496447. doi: 10.1097/00126097-200512000-00006

35. Hildrum B, Romild U, Holmen J. Anxiety and depression lowers blood pressure: 22-year follow-up of the population-based HUNT study, Norway. BMCPublicHealth. 2011;11:601. doi: 10.1186/1471-2458-11-601

36. Janszky I., Ahnve S., Lundberg I et al. Early-onset depression, anxiety, and risk of subsequent coronary heart disease: 37-year follow-up of 49,321 young Swedish men. J. Am. Coll. Cardiol. 2010;56(1):31–37. doi: 10.1016/j.jacc.2010.03.033

37. Oganov R.G., Olbinskaya L.I., Smulevich A.B. and others. Depression and depressive spectrum disorders in general medical practice. Results of the COMPASS program. Cardiology. 2004;1:48-54. (in Russ.)

38. Sandström YK, Ljunggren G, Wändell P, et al. Psychiatric comorbidities in patients with hypertension - a study of registered diagnoses 2009-2013 in the total population in Stockholm County, Sweden. J Hypertens 2016; 34 (3): 414-20. doi: 10.1097/HJH.0000000000000824

39. Smulevich A.B. Depression in psychiatric and medical practices / A.B. Smulevich. — 4<sup>th</sup> ed. — М.: Мedical Informational Agensy, 2015. (in Russ.)

40. Smulevich A.B., Drobizhev M.Yu. Depression in somatic diseases (diagnosis and treatment). RMJ. 1996;1:1. (in Russ.)

41. Zotov P.B., Umansky M.S. Depression in general medical practice: (clinic, diagnosis, drug therapy) : method. manual for doctors. M., 2006. (in Russ.)

42. Kataeva N.G., Kornetov N.A., Alifirova V.M., Levina A.Yu. Post-stroke depression. Advances of modern natural science. 2009;11:91-92. (in Russ.)

43. Fishman B.B., Khoroshevskaya A.I., Abdulin A.A., Semenova G.G., Starikov P.V., Pavlova O.V. Тhe evaluation of compliance to antihypertensive therapy in patients after stroke and poststroke depression during antidepressant therapy. Rational Pharmacotherapy in Cardiology. 2010;6(6):828-831. (In Russ.) doi: 10.20996/1819-6446-2010-6-6-828-831

44. Olenko E.S., Kirichuk V.F., Kodochigova A.I., Kolopkova T.A., Martynova A.G., Subbotina V.G., Sulkovskay L.S., Shumakova A.S. Definition «hypertonic type» persons and it psychophysiological markers. International journal. applied and fundamental research. 2009;(5):119-120. (In Russ.)

45. Géraldine P., Coralie M.G., Georges, A.C. et al. Impact of psychological profile on drug adherence and drug resistance in patients with apparently treatment-resistant hypertension. Blood pressure 2018;37(6):358–367. doi: 10.1080/08037051.2018.1476058

46. Volel B.A., Ternovaya E.S., Ermusheva A.A., Syrkina E.A., Ardzinba I.B. Рersonality disorders and cardiovascular disease (model of coronary heart disease and arterial hypertension). Mental disorders in general medicine. 2014;(1):37-48. (In Russ.)

47. Bodyakin Yu.I., Safronenko A.V. Constitutional and psychotypological features of patients with refractory arterial hypertension. Modern high technology. 2012;(3):52-53. (In Russ.)

48. Smulevich А.B., Ivanov S.V., Myasnikova L.K., Dvoynikov S.Y., Il’ina N.A. Stress-induced dissociation in the trajectory of schizotypal personality disorder (on the model of nosogenias in oncologic patients). S.S. Korsakov Journal of Neurology and Psychiatry. 2014;114(12):12 22.24. (In Russ.) doi: 10.17116/jnevro201411412112-22

49. Andryushchenko A.V. Mental and psychosomatic disorders in institutions of the general somatic network (clinical and epidemiological aspects, psychosomatic relationships, therapy) : abstract. dis. ...cand. honey. Sciences 01/14/06. M., 2011. (In Russ.)

50. Troshina D.V., Volel B.A., Syrkina E.A. Stress-induced atrial fibrillation. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(1):6-13. (In Russ.) doi: 10.17116/jnevro20191190116

51. Smulevich A. B., Syrkin A. L., Drobijev M. Yu., Ivanov S. V. Psychokardiolody. — М.: Medical Informational Agency Ltd., 2006. — 784 р.: ill.

52. Buchina M.M., Kopnina E.I., Chernova M.A. and others. The influence of the degree of increase in blood pressure on the characteristics of perception of life events and coping strategies in patients with hypertension. Bulletin of new medical technologies. 2007;(XIV:2):98-99. (In Russ.)

53. Fofanova T.V., Ageyev F.T., Kadushina E.B., Drobizhev M.Yu., Smirnova M.D., Kuzmina A.E. Psychosomatic Aspects of Low Adherence to Antihypertensive Therapy in Patients with Arterial Hypertension. Systemic Hypertension. 2014;11(3):11-16. (In Russ.)

54. Kozlovsky V.I., Simanovich A.V. Adherence to therapy in patients with stage II arterial hypertension. Literature review and own data. VSMU Bulletin. 2014;(2):6-16. (In Russ.)

55. Pogosova N.V. Depression in cardiac patients: current state of the problem and approaches to treatment. Cardiology. 2004;1:88–92. (In Russ.)

56. Drozdetsky S.I., Kuchin K.V., Makarov V.N. and others. Arterial hypertension and quality of life (anxiety, depression, cognition). Medical almanac. 2011, 3:48-50. (In Russ.)

57. Viktorova I.A., Lisnyak M.V., Akhmedzhanov N.M. Nebieridze D.V. Non-Adherent Behavior in Patients with Anxiety and Hypertension: Focus on Non-Pharmacological Treatment as a Method to Increase Compliance. Rational Pharmacotherapy in Cardiology 2016;12(6):661-668. (In Russ). doi: 10.20996/1819-6446-2016-12-6-661-668

58. Sadreeva S., Zinatullina D. The psychoemotional status of a hypertensive patient in the context of his awareness. Vrach. 2018;29(2):83–86. (In Russ). doi: 10.29296/25877305-2018-02-23


Review

For citations:


Pchelenok J.V., Fomicheva A.V., Kanaeva M., Rodionov A.V., Tolokonin A.O., Volel B.A. The influence of anxiety and depressive disorders on the development of resistant arterial hypertension. Systemic Hypertension. 2024;21(2):51-57. (In Russ.) https://doi.org/10.38109/2075-082X-2024-2-49-55

Views: 446


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2075-082X (Print)
ISSN 2542-2189 (Online)