Functional state of kidneys and arterial hypertension among indigenous and nonindigenous residents of Mountain Shoria

Abstract

Goal: to investigate the interrelation between arterial hypertension and functional state of kidneys among indigenous and nonindigenous Mountain Shoria residents.Material and methods. 370 Mountain Shoria residents (consisting of 113 men and 257 women) were examined. All examinees were 51,07±1,46 and 52,93±0,96 years old on average. The level of blood creatinine was determined by all examinees. Its clearance was calculated according to the Cockcroft-Gault formula in order to determine the glomerular filtration rate. The calculated values were matched with the average square of the body surface (approximately 1,73 square meters). The whole statistical processing was carried out with the help of the Statistica 6.1 programme, significant differences were accepted at p <0,05.Results. 188 people with arterial hypertension were found out among the examined Mountain Shoria residents (this number amounts to 50,81%). The average blood pressure value and the frequency of arterial hypertension among the examinees with renal dysfunction were higher, than among the residents with normal renal function. It was also found out, that the significant reduction of the glomerular filtration rate was typical for the Mountain Shoria residents with arterial hypertension. At the same time the rise in the average level of blood creatinine was noticed only among the women with arterial hypertension. Conclusion. The amount of examinees with the glomerular filtration rate less than 60 ml/min/1,73 sq.m. among the indigenous residents was found to be determinately less than those among the nonindigenous ones, namely 3,65% against 10,67%, by p =0,0082. The amount of examinees with the glomerular filtration rate was proved to be much higher by the patients with arterial hypertension than by the persons with normal blood pressure (11,17% against 2,75%, by p =0,0015). It has been scientifically proved that the average level of blood creatinine by the male examinees was higher, than by the female examinees, and the average value of the glomerular filtration rate was independant upon the sex. The average creatinine level was lower among the indigenous residents than that of the nonindigenous, and the average value of glomerular filtration rate was found out to be higher only by the female indigenous residents.