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Clinical efficacy of sympathetic denervation of renal arteries in patients with resistant arterial hypertension as part of annual prospective follow-up

Abstract

Objective. To study the clinical efficacy of sympathetic denervation of the renal arteries (RDN RA) in patients with resistant arterial hypertension (AH). Materials and methods. The study included 34 patients with resistant AH aged 27 to 70 years. Criteria for inclusion in the research: a resistant course of AH with a level of arterial pressure (BP) >160/100 mm Hg. Art. (With a diuretic) at optimal doses, the preserved renal function (glomerular filtration rate >45 ml/min) and the absence of a secondary form of AH, written informed consent. Results. RDN PA contributed to statistically significant A decrease in both office and average daily SBP and DBP, a clinical hypotensive effect was observed in men and women, however, in the night hours there was a more significant decrease in SBP in women. Conclusions. A prospective one-year observation confirmed a long-term Efficiency RDN RA in the treatment of patients with refractory hypertension.

About the Authors

L. I. Gapon
yumen Cardiology Research Center of the Tomsk National Medical Research Center of the Russian Academy of Sciences
Russian Federation


E. V. Mikova
yumen Cardiology Research Center of the Tomsk National Medical Research Center of the Russian Academy of Sciences
Russian Federation


N. Yu. Savelyeva
yumen Cardiology Research Center of the Tomsk National Medical Research Center of the Russian Academy of Sciences
Russian Federation


G. V. Kolunin
yumen Cardiology Research Center of the Tomsk National Medical Research Center of the Russian Academy of Sciences
Russian Federation


A. Yu. Zherzhova
yumen Cardiology Research Center of the Tomsk National Medical Research Center of the Russian Academy of Sciences
Russian Federation


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Review

For citations:


Gapon L.I., Mikova E.V., Savelyeva N.Yu., Kolunin G.V., Zherzhova A.Yu. Clinical efficacy of sympathetic denervation of renal arteries in patients with resistant arterial hypertension as part of annual prospective follow-up. Systemic Hypertension. 2017;14(2):41-44.

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ISSN 2075-082X (Print)
ISSN 2542-2189 (Online)