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Dynamics of ECG indicators in patients with chronic thromboembolic pulmonary hypertension after transluminal pulmonary balloon angioplasty

https://doi.org/10.26442/2075082X.2019.2.190180

Abstract

Relevance. Chronic thromboembolic pulmonary hypertension is a precapillary form of pulmonary hypertension that develops as a result of the obstruction of the pulmonary arteries by thrombotic masses. Balloon pulmonary angioplasty is an alternative method of treatment of inoperable CTEPH that has demonstrated hemodynamic and clinical effects. In this study we evaluated the relationship between the improvement in hemodynamic and functional status and ECG in patients with CTEPH who underwent BPA treatment. Materials and methods. In 15 patients with CTEPH, we examined the hemodynamic data before and 1 year after BPA. In addition, the sequential ECG findings for right ventricular hypertrophy (RVH) were assessed. Results. There was a significant decrease in all important hemodynamic parameters. Predictors of the improvement in mean PAP were the amplitudes of the S waves in lead V1 and R in lead V5. The width of the QRS complex and the amplitude of the P wave in lead II were identified as significant factors influencing the degree of improvement in the mean PAP. Normalization (<10 mm) of the sum of the amplitudes of the R waves in lead V1 and S in lead V5 are defined as predictors of a higher functional status of the patient in the period after TLA. Conclusion. BPA therapy is reduced pulmonary arterial pressure and improved patients functional status that associated with an improvement in the ECG findings related to RVH which can be used as indicators of the effectiveness of procedure.

About the Authors

M. B. Karabasheva
A.L. Myasnikov Institute of Clinical Cardiology, National Medical Research Center for Cardiology
Russian Federation


N. M. Danilov
A.L. Myasnikov Institute of Clinical Cardiology, National Medical Research Center for Cardiology
Russian Federation


O. V. Sagaidak
A.L. Myasnikov Institute of Clinical Cardiology, National Medical Research Center for Cardiology
Russian Federation


I. G. Matchin
A.L. Myasnikov Institute of Clinical Cardiology, National Medical Research Center for Cardiology
Russian Federation


I. E. Chazova
A.L. Myasnikov Institute of Clinical Cardiology, National Medical Research Center for Cardiology
Russian Federation


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Review

For citations:


Karabasheva M.B., Danilov N.M., Sagaidak O.V., Matchin I.G., Chazova I.E. Dynamics of ECG indicators in patients with chronic thromboembolic pulmonary hypertension after transluminal pulmonary balloon angioplasty. Systemic Hypertension. 2019;16(2):28-31. (In Russ.) https://doi.org/10.26442/2075082X.2019.2.190180

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ISSN 2075-082X (Print)
ISSN 2542-2189 (Online)