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Modern approaches to risk stratification and prognosis assessment in patients with pulmonary arterial hypertension

https://doi.org/10.38109/2075-082X-2026-1-9-16

Abstract

Pulmonary arterial hypertension is a severe progressive disease with a high mortality risk, requiring an accurate prognosis assessment to optimize therapy. Risk stratification plays a key role in predicting survival and choosing treatment tactics. Modern approaches in risk stratification are based on an integrated assessment of clinical, hemodynamic, laboratory and instrumental parameters to identify patients with low, intermediate and high risk of death within 1 year, which allows to personalize treatment: from monotherapy to aggressive combination regimens and referral for transplantation.

About the Authors

Elena A. Karazei
Belarusian State Medical University
Belarus

Elena A. Karazei, Cand. Of Scien. (Med.), Associate Professor, Department of Outpatient Therapy,

83/Bldg. 1, Dzerzhinsky Ave.,  Minsk 220083.



Igor E. Adzerikho
Belarusian State Medical University
Belarus

Igor E. Adzerikho, Dr. Of Scien. (Med.), AProfessor, Department of Clinical Pharmacology and Pharmacotherapy, Institute for Advanced Training and Retraining of Healthcare Personnel,

83/Bldg. 1, Dzerzhinsky Ave.,  Minsk 220083.



Alina A. Кoroliova
Belarusian State Medical University
Belarus

Alina A. Кoroliova, Cand. Of Scien. (Med.), Associate Professor, Department of Clinical Pharmacology, 

83/Bldg. 1, Dzerzhinsky Ave.,  Minsk 220083.



Ludmila V. Karanevich
Healthcare Institution "6th Central District Clinical Polyclinic of the Leninsky District of Minsk"
Belarus

Lyudmila V. Karanevich, Physician, Medical Rehabilitation Department,

5, Ulyanovskaya St., Minsk, 220030.



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For citations:


Karazei E.A., Adzerikho I.E., Кoroliova A.A., Karanevich L.V. Modern approaches to risk stratification and prognosis assessment in patients with pulmonary arterial hypertension. Systemic Hypertension. 2026;23(1):9-16. (In Russ.) https://doi.org/10.38109/2075-082X-2026-1-9-16

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ISSN 2075-082X (Print)
ISSN 2542-2189 (Online)