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Systemic Hypertension

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Vol 16, No 1 (2019)
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CLINICAL GUIDELINES

6-31 957
Abstract

The presented Recommendations are an updated version of the Russian recommendations for the diagnosis and treatment of arterial hypertension from 2016 and foreign recommendations for the treatment of arterial hypertension of the European Society of Hypertension and the European Society of Cardiology from 2018, which, in turn, were created based on the analysis of more than 20 years of experience in large studies of different goals, protocols and volumes conducted on various aspects of the diagnosis and treatment of arterial hypertension. In addition, the sections of the Recommendations devoted to methods of blood pressure control, diagnosis and treatment of AH take into account the experience of domestic studies. The Guidelines set out the basic principles of treatment of patients with hypertension, including in a number of clinical situations that were obtained in randomized controlled trials, at the same time it is important to take into account the individual characteristics of the mechanisms of development and course of the disease, for example, salt sensitivity, secondary hyperaldosteronism in hypertension, individual sensitivity to antihypertensive drugs, which leaves the right and expediency to select antihypertensive therapy in a patient taking into account his individual characteristics.

32-36 404
Abstract
Relevance. Obesity is the main independent risk factor for hypertension (AH). A close association of obesity with arterial pressure has been repeatedly identified in various ethnic, age and gender groups. A direct link between hypertension and various obesity criteria has been studied in many countries and ethnic groups, but the results of studies show that the criterion of obesity, which most accurately predicts the development of hypertension, has not yet been determined. Objective: to evaluate the relationship of different obesity criteria (BMI, WC, WC/HC, level of IV, IVO) to the level of blood pressure and the prevalence of hypertension among the inhabitants of the Siberian region Materials and methods. It was surveyed 1600 people permanently living in the territory of the city of Kemerovo and the Kemerovo region. Statistical processing of data was carried out using the application programs Statistica 6.0. The presence of obesity by various criteria: body mass index (BMI), waist/hip ratio (WC/HC), waist circumference (WC), visceral fat (LV) level, visceral obesity index (IVO). Results. The prevalence of hypertension was 66.2% among men and 66.5% among women (p=0.886). In the obese group, the prevalence of hypertension varied in men from 75.6% (according to the BMI and WC/HC criteria) to 85.9% (visceral fat level), in women from 76.0% (according to WC/HC) to 94.0% (according to the level of visceral fat). In the presence of obesity, according to all the criteria studied, the percentage of a correctly predicted AH was 77.0%, using only one criterion, ranged from 72.7% (LV level) to 75.9% (WC), using two criteria - from 74.4% (BMI+LV level) to 76.3% (WC/HC+WC). Conclusions. The level of blood pressure was influenced by most of the obesity criteria studied, however, the greatest increase in SBP was recorded in the presence of obesity in terms of WC, DBP - in visceral fat. All obesity criteria studied (BMI, WC/HC, WC, IV level, IVO) showed a statistically significant effect on the likelihood of developing hypertension, but more so on BMI (obesity was associated with a 2.15-fold increase in AH).


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ISSN 2075-082X (Print)
ISSN 2542-2189 (Online)