Efficacy of the fixed combination β-blocker and calcium antagonist Logimax at women with an essential hypertension
in different age groups

Efficacy of the fixed combination β-blocker and calcium antagonist Logimax at women with an essential hypertension in different age groups

О. Остроумова, О. Жукова, О. Головина, А. Средняков, А. Отделенов

Abstract

The functional condition of endothelium is investigated at 36 patients with arterial hypertension II-III of a stage (aged 44-80 years) during 3
monthly treatments by fixed combination metoprolol succinate + felodipine (Logimax). Blood pressure (BP) was monitored for 24 hours.
Endothelial vasodilatation function and thickness of a complex intimae - media were evaluated with ultrasonic duplex scanning of arteries. It has
been revealed reduced endothelium-dependent vasodilatation and structural remodeling of peripheral arteries in elderly hypertensives. Alongside
with high antihypertensive activity, indapamid retard positively influenced on structural and functional characteristics of humeral arteries.