«New» molecules composed of rational combinations of antihypertensive drugs: issues of choice
Abstract
The article discusses the factors that determine the choice of antihypertensive drugs, especially blockers of receptors of angiotensin and thiazide diuretics. The data about the peculiarities of azilsartan medoxomil, it differs from other sartans. Among the main properties of azilsartan medoxomil, which may determine his choice for the treatment of patients with arterial hypertension, is called the significant strength of the binding of blockers of receptors of angiotensin to AT1 receptor and its duration of action, as well as special properties that improve tissue sensitivity to insulin. Discussed the feasibility of establishing fixed combinations azilsartan medoxomil with thiazide diuretics chlorthalidone.
About the Authors
O. A. Kislyak
N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Yu. B. Chervyakova
N.I.Pirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Kislyak O.A., Chervyakova Yu.B. «New» molecules composed of rational combinations of antihypertensive drugs: issues of choice. Systemic Hypertension. 2015;12(4):42-45. (In Russ.)
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